81 Result(s)
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Article
Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation
Histone modification through acetylation and deacetylation is a key process in transcription, DNA replication, and chromosome segregation. During mitosis, histones are highly acetylated and chromatin is conden...
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Article
Open AccessElevated matrix metalloproteinase-9 in patients with systemic sclerosis
Matrix metalloproteinase-9 (MMP-9) has been implicated in the pathogenesis of cancer, autoimmune disease, and various pathologic conditions characterized by excessive fibrosis. In this study, we investigated t...
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Decreased incidence of hepatic veno-occlusive disease and fewer hemostatic derangements associated with intravenous busulfan vs oral busulfan in adults conditioned with busulfan + cyclophosphamide for allogeneic bone marrow transplantation
We investigated the occurrence of hepatic veno-occlusive disease (VOD) after allogeneic bone marrow transplantation (BMT) in 241 adults conditioned with busulfan + cyclophosphamide at a single institute and re...
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Article
Is E/E′ reliable in patients with regional wall motion abnormalities to estimate left ventricular filling pressure?
Background There is limited data on the diagnostic utility of the transmitral to mitral annular velocity (E/E′) by tissue Doppler imaging (TDI) in the presence of regional wall motion abnormalities (RWMA). We aim...
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Article
Open AccessAcupuncture for persistent allergic rhinitis: a multi-centre, randomised, controlled trial protocol
Allergic rhinitis is one of the most common health complaints worldwide. Complementary and alternative medical approaches have been employed to relieve allergic rhinitis symptoms and to avoid the side effects ...
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Article
Open AccessAlcohol consumption and carotid artery structure in Korean adults aged 50 years and older
Epidemiologic studies of the association between alcohol consumption and carotid artery structure have reported conflicting results. We investigated the association between alcohol consumption and carotid athe...
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Article
Open AccessAcupuncture for dry eye: a randomised controlled trial protocol
Dry eye is usually managed by conventional medical interventions such as artificial tears, anti-inflammatory drugs and surgical treatment. However, since dry eye is one of the most frequent ophthalmologic diso...
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Article
Prognostic Impact of [18F] FDG-PET in Operable Breast Cancer Treated with Neoadjuvant Chemotherapy
This study aimed to evaluate the usefulness of serial [18F] 2-fluoro-2-deoxy-d-glucose–positron emission tomography ([18F] FDG-PET) in potentially operable breast cancer with neoadjuvant chemotherapy.
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Article
Worse prognosis of metaplastic breast cancer patients than other patients with triple-negative breast cancer
The present study was designed to assess the clinical characteristics and outcomes of metaplastic breast cancer (MBC) compared to general invasive ductal carcinoma (IDC) and the triple-negative subtype (TN-IDC...
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Article
Clinical and imaging findings of systemic hyalinosis: two cases presenting with congenital arthrogryposis
Systemic hyalinosis is a rare, multisystem, progressive, autosomal recessive disorder of connective tissue characterized by diffuse hyaline deposition in the skin, bone or viscera. Owing to its rarity and init...
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Article
Open AccessImpact of Body Mass Index on the relationship of epicardial adipose tissue to metabolic syndrome and coronary artery disease in an Asian population
In a previous study, we demonstrated that the thickness of epicardial adipose tissue (EAT), measured by echocardiography, was increased in patients with metabolic syndrome (MS) and coronary artery disease (CAD...
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Article
Congenital esophageal stenosis associated with esophageal atresia/tracheoesophageal fistula: clinical and radiologic features
Congenital esophageal stenosis (CES) can be associated with esophageal atresia/tracheoesophageal fistula (EA/TEF). Because there are a variety of degrees of obstruction and symptoms of CES, it is frequently di...
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Open AccessAcupuncture for dry eye: a multicentre randomised controlled trial with active comparison intervention (artificial tear drop) using a mixed method approach protocol
Previous studies of acupuncture show favourable results for both subjective and objective outcomes of dry eye. However, firm conclusions could not be drawn from these studies because the quality of the trials ...
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Article
Acculturation, Discrimination and Depressive Symptoms Among Korean Immigrants in New York City
Immigrant mental health issues, especially depression in relation to discrimination and acculturation, are reported to be serious problems in the United States. The current study examines the prevalence of dep...
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Open AccessCumulative smoking exposure, duration of smoking cessation, and peripheral arterial disease in middle-aged and older Korean men
We investigated the association of cumulative smoking exposure and duration of smoking cessation with peripheral arterial disease (PAD).
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Open AccessEvaluation of wet-cup** therapy for persistent non-specific low back pain: a randomised, waiting-list controlled, open-label, parallel-group pilot trial
Persistent non-specific low back pain (PNSLBP) is one of the most frequently experienced types of back pain around the world. Wet-cup** is a common intervention for various pain conditions, especially in Kor...
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Article
Different genetic effect of PXK on systemic lupus erythematosus in the Korean population
PXK was identified as a novel candidate gene for systemic lupus erythematosus (SLE) from genome-wide association studies (GWAS) in Caucasians. But a recent replication study in Hong Kong Chinese reported that ...
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Article
Lack of association between Poly(ADP-ribose) polymerase (PARP) polymorphisms and rheumatoid arthritis in a Korean population
Several studies have investigated the roles of genetic polymorphisms in rheumatoid arthritis (RA). Some of these studies reported that polymorphisms of poly(ADP-ribose) polymerase 1 gene (PARP-1) are linked to rh...
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Article
Robot-Assisted Selective Neck Dissection via Modified Face-lift Approach for Early Oral Tongue Cancer: A Video Demonstration
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Article
Open AccessAssociation of smoking status, cumulative smoking, duration of smoking cessation, age of starting smoking, and depression in Korean adults
Many previous studies did not sufficiently control for several confounding factors that may affect the association between smoking and depression, such as socioeconomic status. We investigated the association ...
