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  1. No Access

    Article

    Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host

    Host adaptation is a key factor contributing to the emergence of new bacterial, viral and parasitic pathogens. Many pathogens are considered promiscuous because they cause disease across a range of host specie...

    Elizabeth J. Klemm, Effrossyni Gkrania-Klotsas, James Hadfield… in Nature Microbiology (2016)

  2. No Access

    Article

    T cell fate and clonality inference from single-cell transcriptomes

    The TraCeR tool extracts full-length, paired T cell receptor sequences from single-cell RNA-sequencing data from T lymphocytes, enabling a combination of clonotype and functional analysis.

    Michael J T Stubbington, Tapio Lönnberg, Valentina Proserpio, Simon Clare… in Nature Methods (2016)

  3. Article

    Open Access

    Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis

    Experimental mouse models are central to basic biomedical research; however, variability exists across genetically identical mice and mouse facilities making comparisons difficult. Whether specific indigenous ...

    Samuel C. Forster, Simon Clare, Benjamin S. Beresford-Jones… in Nature Microbiology (2022)

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