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  1. No Access

    Article

    Adaptation of host transmission cycle during Clostridium difficile speciation

    Bacterial speciation is a fundamental evolutionary process characterized by diverging genotypic and phenotypic properties. However, the selective forces that affect genetic adaptations and how they relate to t...

    Nitin Kumar, Hilary P. Browne, Elisa Viciani, Samuel C. Forster… in Nature Genetics (2019)

  2. Article

    Open Access

    Lentiviral gene therapy rescues p47phox chronic granulomatous disease and the ability to fight Salmonella infection in mice

    Chronic granulomatous disease (CGD) is an inherited primary immunodeficiency disorder characterised by recurrent and often life-threatening infections and hyperinflammation. It is caused by defects of the phag...

    Andrea Schejtman, Walmir Cutrim Aragão-Filho, Simon Clare, Marta Zinicola… in Gene Therapy (2020)

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