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  1. No Access

    Article

    Curcumin Ameliorates Copper-Induced Neurotoxicity Through Inhibiting Oxidative Stress and Mitochondrial Apoptosis in SH-SY5Y Cells

    Impaired homeostasis of copper has been linked to different pathophysiological mechanisms in neurodegenerative diseases and oxidative injury has been proposed as the main mechanism. This study aims to use curc...

    Biao **ang, Daowen Li, Yiqiang Chen, Meng Li, Yuan Zhang, Tun Sun… in Neurochemical Research (2021)

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    Article

    Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis

    Neurotoxicity is an unwanted side-effect seen in patients receiving therapy with the “last-line” polymyxin antibiotics. This is the first study to show that colistin-induced neurotoxicity in neuroblastoma-2a (...

    Chongshan Dai, Giuseppe D. Ciccotosto, Roberto Cappai… in Molecular Neurobiology (2018)

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    Article

    Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy

    Neurotoxicity remains a poorly characterized adverse effect associated with colistin therapy. The aim of the present study was to investigate the mechanism of colistin-induced neurotoxicity using the mouse neu...

    Chongshan Dai, Shusheng Tang, Tony Velkov, **long **ao in Molecular Neurobiology (2016)