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  1. No Access

    Article

    Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis

    Neurotoxicity is an unwanted side-effect seen in patients receiving therapy with the “last-line” polymyxin antibiotics. This is the first study to show that colistin-induced neurotoxicity in neuroblastoma-2a (...

    Chongshan Dai, Giuseppe D. Ciccotosto, Roberto Cappai… in Molecular Neurobiology (2018)

  2. No Access

    Article

    Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy

    Neurotoxicity remains a poorly characterized adverse effect associated with colistin therapy. The aim of the present study was to investigate the mechanism of colistin-induced neurotoxicity using the mouse neu...

    Chongshan Dai, Shusheng Tang, Tony Velkov, **long **ao in Molecular Neurobiology (2016)