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Open AccessZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury
Mitochondria dysfunction contributes to acute liver injuries, and mitochondrial regulators, such as PGC-1α and MCJ, affect liver regeneration. Therefore, identification of mitochondrial modulators may pave the...
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Article
Open AccessIdentification and analysis of the genetic integrity of different types of rice resources through SSR markers
Seed aging is the key factor leading to the loss of genetic integrity. In this study, the seeds of Dongxiang wild rice, **anggu, 9194 and Nipponbare were kept in a plant incubator with constant temperature and...
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Article
Open AccessAsymmetric electron acceptor enables highly luminescent organic solar cells with certified efficiency over 18%
Enhancing the luminescence property without sacrificing the charge collection is one key to high-performance organic solar cells (OSCs), while limited by the severe non-radiative charge recombination. Here, we...
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Article
Open AccessThe δ subunit of F1Fo-ATP synthase is required for pathogenicity of Candida albicans
Fungal infections, especially candidiasis and aspergillosis, claim a high fatality rate. Fungal cell growth and function requires ATP, which is synthesized mainly through oxidative phosphorylation, with the ke...
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Open AccessPublisher Correction: Localized management of non-indigenous animal domesticates in Northwestern China during the Bronze Age
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Open AccessLocalized management of non-indigenous animal domesticates in Northwestern China during the Bronze Age
The movements of ancient crop and animal domesticates across prehistoric Eurasia are well-documented in the archaeological record. What is less well understood are the precise mechanisms that farmers and herde...
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Article
Open AccessUnveiling structure-performance relationships from multi-scales in non-fullerene organic photovoltaics
Unveiling the correlations among molecular structures, morphological characteristics, macroscopic properties and device performances is crucial for develo** better photovoltaic materials and achieving higher...
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Article
Open AccessMemory effect assisted imaging through multimode optical fibres
When light propagates through opaque material, the spatial information it holds becomes scrambled, but not necessarily lost. Two classes of techniques have emerged to recover this information: methods relying ...
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Article
Open AccessComputational optical imaging with a photonic lantern
The thin and flexible nature of optical fibres often makes them the ideal technology to view biological processes in-vivo, but current microendoscopic approaches are limited in spatial resolution. Here, we dem...
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Article
Open AccessDirect analysis in real time-mass spectrometry for rapid quantification of five anti-arrhythmic drugs in human serum: application to therapeutic drug monitoring
Therapeutic drug monitoring (TDM) is necessary for the optimal administration of anti-arrhythmic drugs in the treatment of heart arrhythmia. The present study aimed to develop and validate a direct analysis in...
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Article
Open AccessAerosol-assisted chemical vapour deposition of transparent superhydrophobic film by using mixed functional alkoxysilanes
A method for the preparation of transparent superhydrophobic silica coatings on glass substrates via aerosol‐assisted chemical vapour deposition (AACVD) is described. A multi-layer process to produce dual scal...
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Article
Open AccessDual blockage of both PD-L1 and CD47 enhances immunotherapy against circulating tumor cells
Carcinoma metastasis is triggered by a subpopulation of circulating tumor cells (CTCs). And single immune checkpoint therapy is not good enough to inhibit CTC-induced metastasis. Here, we demonstrate that simu...
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Article
Open AccessA Highly Sensitive Detection System based on Proximity-dependent Hybridization with Computer-aided Affinity Maturation of a scFv Antibody
The hepatitis B virus (HBV) infection is a critical health problem worldwide, and HBV preS1 is an important biomarker for monitoring HBV infection. Previously, we found that a murine monoclonal antibody, mAb-D...
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Article
Open AccessSpexin Suppress Food Intake in Zebrafish: Evidence from Gene Knockout Study
Spexin1 (SPX1) is a newly discovered neuropeptide in vertebrates. Its biological function remains to be elucidated. In this study, we have generated the zebrafish spx1 −/− mutan...
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Open AccessProteomic and network analysis of human serum albuminome by integrated use of quick crosslinking and two-step precipitation
Affinity- and chemical-based methods are usually employed to prepare human serum albuminome; however, these methods remain technically challenging. Herein, we report the development of a two-step precipitation...
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Article
Open AccessDownregulation of ATG5-dependent macroautophagy by chaperone-mediated autophagy promotes breast cancer cell metastasis
Recent data have shown that the expression of lysosome-associated membrane protein type 2 A (LAMP2A), the key protein in the chaperone-mediated autophagy (CMA) pathway, is elevated in breast tumor tissues. How...
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Article
Open AccessEGFR induces DNA decomposition via phosphodiester bond cleavage
EGFR may induce DNA degradation. This activity had not been previously described as an EGRF function. To confirm this unexpected activity, testing of EGFR in the presence of ATP and either 5A, 5C, 5G, 5T, or 5...
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Article
Open AccessAdaptive free-space optical communications through turbulence using self-healing Bessel beams
We present a scheme to realize obstruction- and turbulence-tolerant free-space orbital angular momentum (OAM) multiplexing link by using self-healing Bessel beams accompanied by adaptive compensation technique...
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Open AccessHeterophase-structured nanocrystals as superior supports for Ru-based catalysts in selective hydrogenation of benzene
ZrO2 heterophase structure nanocrystals (HSNCs) were synthesized with tunable ratios of monoclinic ZrO2 (m-ZrO2) to tetragonal ZrO2 (t-ZrO2). The phase mole ratio of m-ZrO2 versus t-ZrO2 in ZrO2 HSNCs was tuned f...
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Open AccessFull-duplex bidirectional data transmission link using twisted lights multiplexing over 1.1-km orbital angular momentum fiber
We present a full-duplex bidirectional data transmission link using twisted lights multiplexing over 1.1-km orbital angular momentum (OAM) fiber. OAM+1 and OAM−1 modes carrying 20-Gbit/s quadrature phase-shift ke...