-
Article
Open AccessGlobal prototype distillation for heterogeneous federated learning
Federated learning is a distributed machine learning paradigm where the goal is to collaboratively train a high quality global model while private training data remains local over distributed clients. However,...
-
Article
Open AccessEffect of cytokines on advanced hepatocellular carcinoma prognosis receiving radiotherapy and tislelizumab plus anlotinib: a single-center phase II clinical trial
The purpose of this study was to investigate the relationship between circulating cytokines and liver function and prognosis of patients with advanced hepatocellular carcinoma (HCC) treated with radiotherapy c...
-
Article
Open AccessIC100, a humanized therapeutic monoclonal anti-ASC antibody alleviates oxygen-induced retinopathy in mice
Retinopathy of prematurity (ROP), which often presents with bronchopulmonary dysplasia (BPD), is among the most common morbidities affecting extremely premature infants and is a leading cause of severe vision ...
-
Article
Open AccessCorrection to: Dominant‑negative transforming growth factor‑β receptor‑armoured mesothelin‑targeted chimeric antigen receptor T cells slow tumour growth in a mouse model of ovarian cancer
-
Article
Correction: THUMPD3-AS1 facilitates cell growth and aggressiveness by the miR-218-5p/SKAP1 axis in colorectal cancer
-
Article
Open AccessChorioamnionitis accelerates granule cell and oligodendrocyte maturation in the cerebellum of preterm nonhuman primates
Preterm birth is often associated with chorioamnionitis and leads to increased risk of neurodevelopmental disorders, such as autism. Preterm birth can lead to cerebellar underdevelopment, but the mechanisms of...
-
Chapter and Conference Paper
Molecular Dynamics Simulation Study of Hydrogen Hydrate Formation in the Presence of Electric Field
The electric field plays a significant role in the induction of natural gas hydrate formation, leading to its rapid generation. This study investigates the formation of hydrogen gas hydrates under different el...
-
Article
Open AccessProtective role of CXCR7 activation in neonatal hyperoxia-induced systemic vascular remodeling and cardiovascular dysfunction in juvenile rats
Neonatal hyperoxia induces long-term systemic vascular stiffness and cardiovascular remodeling, but the mechanisms are unclear. Chemokine receptor 7 (CXCR7) represents a key regulator of vascular homeostasis a...
-
Article
PGC-1α Inhibits Schwann Cell Dedifferentiation and Delays Peripheral Nerve Degeneration by Targeting PON1
PPARγ coactivator-1 alpha (PGC-1α) is an essential transcription factor co-activator that regulates gene transcription and neural regeneration. Schwann cells, which are unique glial cells in peripheral nerves ...
-
Article
Open AccessGSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice
Neonatal hyperoxia exposure is associated with brain injury and poor neurodevelopment outcomes in preterm infants. Our previous studies in neonatal rodent models have shown that hyperoxia stimulates the brain’...
-
Article
A Blockchain-Assisted Lightweight Anonymous Authentication Scheme for Medical Services in Internet of Medical Things
Internet of medical things (IoMT) enable physicians to provide precise care on the Internet for registered patients anywhere, bringing convenience to people’s everyday life. Considering the importance of patie...
-
Article
Open AccessAI in Human-computer Gaming: Techniques, Challenges and Opportunities
With the breakthrough of AlphaGo, human-computer gaming AI has ushered in a big explosion, attracting more and more researchers all over the world. As a recognized standard for testing artificial intelligence,...
-
Article
Open AccessDominant-negative transforming growth factor-β receptor-armoured mesothelin-targeted chimeric antigen receptor T cells slow tumour growth in a mouse model of ovarian cancer
Ovarian cancer is a major cause of death among all gynaecological cancers. Although surgery, chemotherapy and targeted therapy have yielded successful outcomes, the 5-year survival rate remains < 30%. Adoptive...
-
Article
An integrative analysis of enhancer of yellow 2 homolog (ENY2) as a molecular biomarker in pan-cancer
ENY2 (Enhancer of yellow 2 transcription factor) is a transcription nuclear protein and primarily participates in the course of mRNA export and histone deubiquitination to influence gene expression. Current st...
-
Article
Electrochemical determination of benomyl using MWCNTs interspersed graphdiyne as enhanced electrocatalyst
Graphdiyne (GDY) has attracted a lot of interest in electrochemical sensing application with the advantages of a large conjugation system, porous structure, and high structure defects. Herein, to further impro...
-
Article
A sensitive fluorescence detection strategy for H2O2 and glucose by using aminated Fe–Ni bimetallic MOF as fluorescent nanozyme
An aminated Fe–Ni bimetallic metal–organic framework (Fe3Ni-MOF-NH2) with both peroxidase-like activity and fluorescence properties was developed. Fe3Ni-MOF-NH2 possessed the enhanced peroxidase-like activity thr...
-
Article
Open AccessGSDMD deficiency ameliorates hyperoxia-induced BPD and ROP in neonatal mice
Bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) are among the most common morbidities affecting extremely premature infants who receive oxygen therapy. Many clinical studies indicate that...
-
Article
Failure behavior and energy evolution characteristics of deep roadway sandstone under different microwave irradiation modes
Efficient breaking of hard rock and prevention and control of rock burst disasters are two key concerns for construction in deep areas with high in-situ stresses and are two of the most important ways to ensur...
-
Chapter and Conference Paper
Condition Monitoring Method for Bridge Crane Equipment Based on BIM Technology and Bayesian Theory
To improve the monitoring efficiency while reducing costs for process control, a bridge crane equipment health condition monitoring method in conjunction with a variable sampling interval (VSI) Bayesian defect...
-
Article
Open AccessSupplementing the early diet of broilers with soy protein concentrate can improve intestinal development and enhance short-chain fatty acid-producing microbes and short-chain fatty acids, especially butyric acid
Research on nutrition in early-life commonly focuses on the maturation of the intestine because the intestinal system is crucial for ensuring continued growth. To explore the importance of early nutrition regu...
