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Article
Hsa_circ_0084912 Drives the Progression of Cervical Cancer Via Regulating miR-429/SOX2 Pathway
We focus on hsa_circ_0084912’s role in Cervical cancer (CC) and its molecular pathways. In order to determine the expression of Hsa_circ_0084912, miR-429, and SOX2 in CC tissues and cells, Western blotting and...
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Article
Exploration of Whole Blood Chromium as Biomarker of Hexavalent Chromium Exposure: Based on Literature Review and Monte Carlo Simulation
Hexavalent chromium (Cr(VI)) is a sort of common industrial poison and environmental pollutant posing great health threat to the population. Appropriate biomarkers are indispensable indicative tools in the bio...
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Article
Open AccessActive and stable alcohol dehydrogenase-assembled hydrogels via synergistic bridging of triazoles and metal ions
Biocatalysis is increasingly replacing traditional methods of manufacturing fine chemicals due to its green, mild, and highly selective nature, but biocatalysts, such as enzymes, are generally costly, fragile,...
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Article
Local palliative therapies for unresectable malignant biliary obstruction: radiofrequency ablation combined with stent or biliary stent alone? An updated meta-analysis of nineteen trials
Recently, there has been a burgeoning interest in radiofrequency ablation combined with stent (RFA + Stent) for unresectable malignant biliary obstruction (MBO). This study aimed to perform a meta-analysis to ...
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Article
Proximal Gastrectomy Versus Total Gastrectomy for Siewert II/III Adenocarcinoma of the Gastroesophageal Junction: a Systematic Review and Meta-analysis
The incidence of adenocarcinoma of the esophagogastric junction (AEG) has rapidly increased in recent years. Popular surgical approaches for AEG are proximal gastrectomy (PG) and total gastrectomy (TG), but it...
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Article
Clinical efficacy and safety of robotic distal gastrectomy for gastric cancer: a systematic review and meta-analysis
Robotic distal gastrectomy (RDG) is a new technique that is rapidly gaining popularity and may help overcome the limitations of laparoscopic distal gastrectomy (LDG); however, its safety and therapeutic effica...
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Article
Open AccessA 6.3 Mb maternally derived microduplication of 20p13p12.2 in a fetus with Brachydactyly type D and related literature review
With the introduction of genetic tests such as chromosomal microarray analysis (CMA) and exome sequencing (ES) into fetal medical practices, genotype–phenotype correlations in intrauterine-onset disorders have...
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Article
Reduction of risk of infection during elective laparoscopic cholecystectomy using prophylactic antibiotics: a systematic review and meta-analysis
Whether perioperative administration is required in elective laparoscopic cholecystectomy (LC) in patients with low risk of infection remains controversial.
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Article
Open AccessImmune checkpoint blockade in the treatment of malignant tumor: current statue and future strategies
After being stagnant for decades, there has finally been a paradigm shift in the treatment of cancer with the emergence and application of immune checkpoint inhibitors (ICIs). The most extensively utilized ICI...
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Article
Comparison of intraoperative endoscopic retrograde cholangiopancreatography and laparoscopic common bile duct exploration combined with laparoscopic cholecystectomy for treating gallstones and common bile duct stones: a systematic review and meta-analysis
This study aimed to compare the efficacy and safety of laparoscopic cholecystectomy combined with intraoperative endoscopic retrograde cholangiopancreatography (LC-IntraERCP) and laparoscopic cholecystectomy c...
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Article
Cell membrane damage induced by continuous stress of artemisinin sustained-release microspheres (ASMs) on Microcystis aeruginosa at different physiological stages
Artemisinin sustained-release microspheres (ASMs) with long-term inhibition effects (> 40 days) on harmful freshwater bloom-forming cyanobacteria have been found in previous studies, but the inhibition mechani...
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Chapter and Conference Paper
Evaluation of Three Analytical Solar Chimney Models with Field Data
The paper reported the measured airflow rates in a solar chimney installed on a detached test house in Hangzhou. The one-week data showed that in addition to buoyancy flow enforced by the solar radiation, sign...
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Article
Effects of cyanobacteria decomposition on the remobilization and ecological risk of heavy metals in Taihu Lake
To investigate the relationship between cyanobacteria decomposition and the remobilization of heavy metals in Taihu Lake, the indoor simulation experiments were conducted. The areas of Taihu Lake that undergo ...
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Article
Annual energy performance simulation of solar chimney in a cold winter and hot summer climate
The paper studies the energy performance of a solar chimney (SC) in a high performance two-story detached house with 220 m2 floor area using EnergyPlus and the climate data of the hot summer and cold winter in Ch...
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Article
Open AccessDescription of the molecular and phenotypic spectrum of Wiedemann-Steiner syndrome in Chinese patients
Wiedemann–Steiner syndrome (WDSTS) is a rare genetic disorder characterized by facial gestalt, neurodevelopmental delay, skeletal anomalies and growth retardation, which is caused by variation of KMT2A gene. To d...
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Article
Open AccessA novel TSC2 missense variant associated with a variable phenotype of tuberous sclerosis complex: case report of a Chinese family
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by the development of hamartomas in multiple organs, including the brain, heart, skin, kidney, lung and retina. A diagno...
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Chapter and Conference Paper
Design and Analysis of Double-Arc Tooth Profile Harmonic Drive
Harmonic drive show an extraordinary transmission characteristic with high with high efficiency and attract considerable attention. In this article, a double-arc tooth profile harmonic drive was designed. An ...
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Article
Characterization of extracellular polymeric substance (EPS) fractions produced by Microcystis aeruginosa under the stress of linoleic acid sustained-release microspheres
This paper focuses on the characterization of extracellular polymeric substances (EPS), which are composed of soluble EPS (SL-EPS), loosely bound EPS (LB-EPS), and tightly bound EPS (TB-EPS) produced by Microcyst...
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Article
Multienzymatic cascade synthesis of fucosyloligosaccharide via a two-step fermentation strategy in Escherichia coli
To achieve multienzymatic cascade synthesis of fucosyl oligosaccharide from d-mannose by two-step fermentation pathway in Escherichia coli.
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Article
Effects of cutoff thresholds for minor allele frequencies on HapMap resolution: A real dataset-based evaluation of the Chinese Han and Tibetan populations
Genomic variation is the genetic basis of phenotypic diversity among individuals, including variation in disease susceptibility and drug response. The greatest promise of the International HapMap is to provide...