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Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy

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  1. Article

    Open Access

    Conserved protein Pir2ARS2 mediates gene repression through cryptic introns in lncRNAs

    Long non-coding RNAs (lncRNAs) are components of epigenetic control mechanisms that ensure appropriate and timely gene expression. The functions of lncRNAs are often mediated through associated gene regulatory...

    Gobi Thillainadesan, Hua **ao, Sahana Holla, Jothy Dhakshnamoorthy… in Nature Communications (2020)

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  2. Article

    Open Access

    A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing

    Gene regulatory mechanisms rely on a complex network of RNA processing factors to prevent untimely gene expression. In fission yeast, the highly conserved ortholog of human ERH, called Erh1, interacts with the...

    Guodong **e, Tommy V. Vo, Gobi Thillainadesan, Sahana Holla… in Nature Communications (2019)

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