13 Result(s)
within
Shin Jung
Neurosciences
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Article
Cell surface aggregation of elastin receptor molecules caused by suramin amplified signals leading to proliferation of human glioma cells
We have recently shown that glioma cell lines, as well as cells of human malignant gliomas in situ, synthesize tropoelastin. In addition, glioma cells degrade tropoelastin using metalloproteinase(s), and the ...
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Article
Cervical dermal sinus associated with dermoid cyst
We report a rare case of cervical dermal sinus associated with a dermoid cyst in a 10-month-old infant, who presented with a 1-month history of motor weakness of the right upper extremity. Magnetic resonance i...
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Article
Metastatic spinal cord compression of testicular yolk sac tumor
Introduction: Pediatric testicular tumors are rare. Spinal metastasis of testicular yolk sac tumor (YST) is extremely rare, with only one reported case. Case report: We report a rare case of meta...
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Clinical features and epileptogenesis of dysembryoplastic neuroepithelial tumor
Dysembryoplastic neuroepithelial tumor (DNT) frequently causes medically intractable epilepsy.
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Prognostic significance of neuronal marker expression in glioblastomas
Glioblastomas are the most malignant tumors of central nervous system neoplasms and are well known for their biological heterogeneity. Contrary to the putative hypothesis of purely glial differentiation in gli...
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Open AccessTERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
Telomerase reverse transcriptase (TERT) promoter mutations were recently shown to drive telomerase activity in various cancer types, including medulloblastoma. However, the clinical and biologica...
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Article
Solitary Langerhans cell histocytosis of skull and spine in pediatric and adult patients
Langerhans cell histiocytosis (LCH) is a rare neoplasm and has heterogeneous clinical presentation and behavior. We analyzed solitary lytic lesions of the skull and spine in pediatric and adult patients.
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Open AccessWNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma
TP53 mutations confer subgroup specific poor survival for children with medulloblastoma. We hypothesized that WNT activation which is associated with improved survival for such children abrogates TP53 related ra...
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Differences in the clinical courses of pediatric and adult pilocytic astrocytomas with progression: a single-institution study
Pilocytic astrocytoma (PA) is a World Health Organization grade I neoplasm that generally follows a benign course. However, in some patients, PA exhibits an aggressive clinical course. Here, we examined the cl...
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Article
Visual outcome after endoscopic third ventriculostomy for hydrocephalus
Hydrocephalus-related symptoms are mostly improved after successful endoscopic third ventriculostomy (ETV). However, visual symptoms can be different. This study was focused on visual symptoms. We analyzed the...
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Article
Heterogeneity within the PF-EPN-B ependymoma subgroup
Posterior fossa ependymoma comprise three distinct molecular variants, termed PF-EPN-A (PFA), PF-EPN-B (PFB), and PF-EPN-SE (subependymoma). Clinically, they are very disparate and PFB tumors are currently bei...
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Article
The Role Played by SLUG, an Epithelial–Mesenchymal Transition Factor, in Invasion and Therapeutic Resistance of Malignant Glioma
In malignant gliomas, invasive phenotype and cancer stemness promoting resurgence of residual tumor cells render treatment very difficult. Hence, identification of epithelial–mesenchymal transition (EMT) facto...
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Subgroup and subtype-specific outcomes in adult medulloblastoma
Medulloblastoma, a common pediatric malignant central nervous system tumour, represent a small proportion of brain tumours in adults. Previously it has been shown that in adults, Sonic Hedgehog (SHH)-activated...
