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Obtained transgenic wheat expressing pac1 mediated by Agrobacterium is resistant against Barley yellow dwarf virus-GPV
In fission yeast (Schizosaccharomyces pombe), pac1 gene was cloned with 99.3% nucleotide sequence similarity with published pac1 in GenBank. In pET-5α expression system, the expression product of cloned pac1 in E...
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Article
Open AccessTGF-β1, IL-6 and TNF-α in Bronchoalveolar Lavage Fluid: Useful Markers for Lung Cancer?
Changes of cytokines in bronchoalveolar lavage fluid (BALF) reflect immunologic reactions of the lung in pulmonary malignancies. Detection of biomarkers in BALF might serve as an important method for different...
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Article
Open AccessThe construction of hierarchical structure on Ti substrate with superior osteogenic activity and intrinsic antibacterial capability
The deficient osseointegration and implant-associated infections are pivotal issues for the long-term clinical success of endosteal Ti implants, while development of functional surfaces that can simultaneously...
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Article
Open AccessFunctional polymorphisms in the promoter region of MMP-2 and MMP-9 and susceptibility to obstructive sleep apnea
Genetic susceptibility to obstructive sleep apnea (OSA) has been a research focus in the scientific community in the past few years. In this study, we recruited 375 subjects to investigate whether functional p...
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Article
Open AccessDNA methylation Landscape of body size variation in sheep
Sub-populations of Chinese Mongolian sheep exhibit significant variance in body mass. In the present study, we sequenced the whole genome DNA methylation in these breeds to detect whether DNA methylation plays...
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Article
Open AccessBiological and immunotoxicity evaluation of antimicrobial peptide-loaded coatings using a layer-by-layer process on titanium
The prevention and control of peri-implantitis is a challenge in dental implant surgery. Dental implants with sustained antimicrobial coating are an ideal way of preventing peri-implantitis. This study reports...
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Article
Open AccessThe autism-related gene SNRPN regulates cortical and spine development via controlling nuclear receptor Nr4a1
The small nuclear ribonucleoprotein polypeptide N (SNRPN) gene, encoding the RNA-associated SmN protein, duplications or deletions of which are strongly associated with neurodevelopmental disabilities. SNRPN-codi...
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Article
Superparamagnetic enhancement of thermoelectric performance
By embedding superparamagnetic nanoparticles in a thermoelectric matrix, phonon and electron transport within the material can be controlled simultaneously at nanometre and mesoscopic length scales, thereby im...
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Article
Open AccessDeep sequencing reveals the first fabavirus infecting peach
A disease causing smaller and cracked fruit affects peach [Prunus persica (L.) Batsch], resulting in significant decreases in yield and quality. In this study, peach tree leaves showing typical symptoms were subj...
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Article
Open AccessTGF-β1-induced miR-503 controls cell growth and apoptosis by targeting PDCD4 in glioblastoma cells
Aberrant expression of microRNAs hae been shown to be closely associated with glioblastoma cell proliferation, apoptosis and drug resistance. However, mechanisms underlying the role of mcroRNAs in glioblastoma...
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Correction: Corrigendum: Superparamagnetic enhancement of thermoelectric performance
Nature 549, 247–251 (2017); doi:10.1038/nature23667 In the Methods subsection ‘Measure the Hall coefficient’ of this Letter, the equation μH = neσ should read μH = σ/(ne). This error has been corrected online.
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Open AccessAuthor Correction: Deep sequencing reveals the first fabavirus infecting peach
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
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Article
Open AccessAuthor Correction: TGF-β1-induced miR-503 controls cell growth and apoptosis by targeting PDCD4 in glioblastoma cells
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Article
Open AccessAnalyses of virus/viroid communities in nectarine trees by next-generation sequencing and insight into viral synergisms implication in host disease symptoms
We analyzed virus and viroid communities in five individual trees of two nectarine cultivars with different disease phenotypes using next-generation sequencing technology. Different viral communities were foun...
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Article
Open AccessInfluence of InP coupling cavity on Fano resonance of sub wavelength MIM waveguide
In this paper, influence of InP coupling cavity on Fano resonance of sub wavelength MIM waveguide was studied by FDTD. It was observed that the resonant wavelengths of mode mj (j = 1, 2, 3) were closely related w...
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Article
Open AccessUnique DUOX2+ACE2+ small cholangiocytes are pathogenic targets for primary biliary cholangitis
Cholangiocytes play a crucial role in bile formation. Cholangiocyte injury causes cholestasis, including primary biliary cholangitis (PBC). However, the etiology of PBC remains unclear despite being characteri...
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Open AccessThe inhibitory effect and mechanism of Resina Draconis on the proliferation of MCF-7 breast cancer cells: a network pharmacology-based analysis
Resina Draconis (RD) is known as the "holy medicine for promoting blood circulation" and possesses antitumor properties against various types of cancer, including breast cancer (BC); however, the underlying me...
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Article
Open AccessApplication of a linear interpolation algorithm in radiation therapy dosimetry for 3D dose point acquisition
Air-vented ion chambers are generally used in radiation therapy dosimetry to determine the absorbed radiation dose with superior precision. However, in ion chamber detector arrays, the number of array elements...
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Article
Open AccessTunable backbone-degradable robust tissue adhesives via in situ radical ring-opening polymerization
Adhesives with both robust adhesion and tunable degradability are clinically and ecologically vital, but their fabrication remains a formidable challenge. Here we propose an in situ radical ring-opening polyme...
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Open AccessHeparin-network-mediated long-lasting coatings on intravascular catheters for adaptive antithrombosis and antibacterial infection
Bacteria-associated infections and thrombosis, particularly catheter-related bloodstream infections and catheter-related thrombosis, are life-threatening complications. Herein, we utilize a concise assembly of...