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Using network pharmacological analysis and molecular docking to investigate the mechanism of action of quercetin’s suppression of oral cancer

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  1. Article

    Open Access

    Combination therapy with oncolytic viruses and immune checkpoint inhibitors in head and neck squamous cell carcinomas: an approach of complementary advantages

    Squamous cell carcinomas are the most common head and neck malignancies. Significant progress has been made in standard therapeutic methods combining surgery, radiation, and chemotherapy. Nevertheless, the 5-y...

    Hui Dong, Mengli Li, Chen Yang, Wei Wei, **anglei He in Cancer Cell International (2023)

  2. Article

    Open Access

    The correlation of fibrinogen-like protein-1 expression with the progression and prognosis of hepatocellular carcinoma

    Fibrinogen-like-protein 1 (FGL1), a member of the fibrinogen-related protein (FREP) family, is a major ligand of the immune inhibitory receptor lymphocyte-activation gene 3 (LAG-3). While FGL1 is strongly impl...

    Nanni Hua, Anxian Chen, Chen Yang, Hui Dong, **anglei He in Molecular Biology Reports (2022)

  3. Article

    Open Access

    CD19-targeted BiTE expression by an oncolytic vaccinia virus significantly augments therapeutic efficacy against B-cell lymphoma

    Immunotherapy with CD19-targeting bispecific T-cell engagers (CD19BiTEs) has demonstrated highly effective killing of cancer cells in patients with precursor acute lymphoblastic leukemia and non-Hodgkin’s lymp...

    Wen Lei, Qian Ye, Yuanyuan Hao, Jie Chen, Yu Huang, Liu Yang in Blood Cancer Journal (2022)

  4. Article

    Open Access

    Nanocarriers surface engineered with cell membranes for cancer targeted chemotherapy

    Inspired by nature, the biomimetic approach has been incorporated into drug nanocarriers for cancer targeted chemotherapy. The nanocarriers are cloaked in cell membranes, which enables them to incorporate the ...

    Wen Lei, Chen Yang, Yi Wu, Guoqing Ru, **anglei He in Journal of Nanobiotechnology (2022)

  5. Article

    Open Access

    A review on the advances and challenges of immunotherapy for head and neck cancer

    Head and neck cancer (HNC), which includes lip and oral cavity, larynx, nasopharynx, oropharynx, and hypopharynx malignancies, is one of the most common cancers worldwide. Due to the interaction of tumor cells...

    Gang Cheng, Hui Dong, Chen Yang, Yang Liu, Yi Wu, Lifen Zhu in Cancer Cell International (2021)

  6. Article

    Open Access

    Combined expression of miR-34a and Smac mediated by oncolytic vaccinia virus synergistically promote anti-tumor effects in Multiple Myeloma

    Despite great progress made in the treatment of multiple myeloma (MM), it is still incurable. Promising phase II clinical results have been reported recently for oncolytic vaccinia virus (OVV) clinic therapeut...

    Wen Lei, Shibing Wang, Chunmei Yang, **anbo Huang, Zhenzhen Chen in Scientific Reports (2016)

  7. Article

    Open Access

    Signature of a polyamorphic transition in the THz spectrum of vitreous GeO2

    The THz spectrum of density fluctuations, S(Q, ω), of vitreous GeO2 at ambient temperature was measured by inelastic x-ray scattering from ambient pressure up to pressures well beyond that of the known α-quartz t...

    Alessandro Cunsolo, Yan Li, Chaminda N. Kodituwakku, Shibing Wang in Scientific Reports (2015)

  8. Article

    Open Access

    Pressure induced metallization with absence of structural transition in layered molybdenum diselenide

    Layered transition-metal dichalcogenides have emerged as exciting material systems with atomically thin geometries and unique electronic properties. Pressure is a powerful tool for continuously tuning their cr...

    Zhao Zhao, Haijun Zhang, Hongtao Yuan, Shibing Wang, Yu Lin in Nature Communications (2015)