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    Article

    Hepatocyte-derived MANF mitigates ethanol-induced liver steatosis in mice via enhancing ASS1 activity and activating AMPK pathway

    Hepatic steatosis plays a detrimental role in the onset and progression of alcohol-associated liver disease (ALD). Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an evolutionarily conserved prot...

    Han-yang Xu, Yan-hong Jiao, Shi-yu Li, Xu Zhu, Sheng Wang in Acta Pharmacologica Sinica (2023)

  2. Article

    Open Access

    Collagen fiber features and COL1A1: are they associated with elastic parameters in breast lesions, and can COL1A1 predict axillary lymph node metastasis?

    This study aimed to explore whether collagen fiber features and collagen type I alpha 1 (COL1A1) are related to the stiffness of breast lesions and whether COL1A1 can predict axillary lymph node metastasis (LNM).

    Ying Jiang, Bo Wang, Jun Kang Li, Shi Yu Li, Rui Lan Niu, Nai Qin Fu in BMC Cancer (2022)

  3. Article

    Open Access

    TGF-β1 and its signal molecules: are they correlated with the elasticity characteristics of breast lesions?

    Shear wave elastography can evaluate tissue stiffness. Previous studies showed that the elasticity characteristics of breast lesions were related to the components of extracellular matrix which was regulated b...

    Meng Ke Zhang, Bo Wang, Shi Yu Li, Gang Liu, Zhi Li Wang in BMC Cancer (2021)