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Metabolomic signatures for blood pressure from early to late adolescence: findings from a U.S. cohort

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  1. Article

    Open Access

    Associations of prenatal maternal depressive symptoms with cord blood glucocorticoids and child hair cortisol levels in the project viva and the generation R cohorts: a prospective cohort study

    Prior studies have reported conflicting results regarding the association of prenatal maternal depression with offspring cortisol levels. We examined associations of high levels of prenatal depressive symptoms...

    Nathan J. Cohen, Serena Defina, Sheryl L. Rifas-Shiman in BMC Pediatrics (2023)

  2. Article

    Open Access

    Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude

    Seasonal variations in environmental exposures at birth or during gestation are associated with numerous adult traits and health outcomes later in life. Whether DNA methylation (DNAm) plays a role in the molec...

    Latha Kadalayil, Md. Zahangir Alam, Cory Haley White in Clinical Epigenetics (2023)

  3. Article

    Open Access

    Author Correction: Genetic effects on the timing of parturition and links to fetal birth weight

    Pol Solé-Navais, Christopher Flatley, Valgerdur Steinthorsdottir in Nature Genetics (2023)

  4. Article

    Open Access

    DNA methylation age at birth and childhood: performance of epigenetic clocks and characteristics associated with epigenetic age acceleration in the Project Viva cohort

    Epigenetic age acceleration (EAA) and epigenetic gestational age acceleration (EGAA) are biomarkers of physiological development and may be affected by the perinatal environment. The aim of this study was to e...

    Anne K. Bozack, Sheryl L. Rifas-Shiman, Diane R. Gold in Clinical Epigenetics (2023)

  5. Article

    Open Access

    Genetic effects on the timing of parturition and links to fetal birth weight

    The timing of parturition is crucial for neonatal survival and infant health. Yet, its genetic basis remains largely unresolved. We present a maternal genome-wide meta-analysis of gestational duration (n = 195,55...

    Pol Solé-Navais, Christopher Flatley, Valgerdur Steinthorsdottir in Nature Genetics (2023)

  6. Article

    Open Access

    Adolescent overeating and binge eating behavior in relation to subsequent cardiometabolic risk outcomes: a prospective cohort study

    Binge eating disorder is bidirectionally associated with obesity and with metabolic syndrome. It is less clear whether overeating and binge eating, or overeating with loss of control, also predicts metabolic r...

    Joyce C. Zhou, Sheryl L. Rifas-Shiman, Jess Haines in Journal of Eating Disorders (2022)

  7. Article

    Open Access

    Association of total lifetime breastfeeding duration with midlife handgrip strength: findings from Project Viva

    Lactation has long term effects on maternal health, but the relationship between lactation and long-term handgrip strength, a marker of musculoskeletal function and healthy aging, has not been explored.

    Irasema C. Paster, Pi-i D. Lin, Sheryl L. Rifas-Shiman, Wei Perng in BMC Women's Health (2022)

  8. Article

    Open Access

    History of infertility and pregnancy outcomes in Project Viva: a prospective study

    Infertility has been associated with the risk of adverse pregnancy outcomes. It is not clear whether infertility and underlying causes of infertility or the use of medically assisted reproduction (MAR) therapi...

    Diana C. Soria-Contreras, Wei Perng, Sheryl L. Rifas-Shiman in BMC Pregnancy and Childbirth (2022)

  9. Article

    Open Access

    Longitudinal associations of DNA methylation and sleep in children: a meta-analysis

    Sleep is important for healthy functioning in children. Numerous genetic and environmental factors, from conception onwards, may influence this phenotype. Epigenetic mechanisms such as DNA methylation have bee...

    Sara Sammallahti, M. Elisabeth Koopman-Verhoeff, Anne-Claire Binter in Clinical Epigenetics (2022)

  10. Article

    Open Access

    Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills

    Cognitive skills are a strong predictor of a wide range of later life outcomes. Genetic and epigenetic associations across the genome explain some of the variation in general cognitive abilities in the general...

    Doretta Caramaschi, Alexander Neumann, Andres Cardenas in Molecular Psychiatry (2022)

  11. Article

    Open Access

    Cesarean delivery and metabolic health and inflammation biomarkers during mid-childhood and early adolescence

    We assessed differences in plasma levels of metabolic health and inflammation biomarkers during mid-childhood and early adolescence between children born by cesarean section vs. vaginal delivery.

    Lidia Mínguez-Alarcón, Sheryl L. Rifas-Shiman, Caroline Mitchell in Pediatric Research (2022)

  12. Article

    Open Access

    Prenatal metal exposure, cord blood DNA methylation and persistence in childhood: an epigenome-wide association study of 12 metals

    Prenatal exposure to essential and non-essential metals impacts birth and child health, including fetal growth and neurodevelopment. DNA methylation (DNAm) may be involved in pathways linking prenatal metal ex...

    Anne K. Bozack, Sheryl L. Rifas-Shiman, Brent A. Coull in Clinical Epigenetics (2021)

  13. Article

    Open Access

    DNA methylation architecture of the ACE2 gene in nasal cells of children

    Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has led to the global coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2 enters cells via angiotensin-Converting Enzyme 2 (ACE2) receptors, hi...

    Andres Cardenas, Sheryl L. Rifas-Shiman, Joanne E. Sordillo in Scientific Reports (2021)

  14. Article

    Open Access

    Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

    Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal development, we investigated...

    Simon Kebede Merid, Alexei Novoloaca, Gemma C. Sharp, Leanne K. Küpers in Genome Medicine (2020)

  15. Article

    Open Access

    Women’s perceived social support: associations with postpartum weight retention, health behaviors and depressive symptoms

    Social support may promote healthful behaviors that prevent excess weight at critical periods in women’s life. Our objective was to investigate associations of social support at 6 months postpartum with women’...

    Sabrina Faleschini, Lynne Millar, Sheryl L. Rifas-Shiman in BMC Women's Health (2019)

  16. Article

    Open Access

    Evaluation of the impact of calorie labeling on McDonald’s restaurant menus: a natural experiment

    The long-term effect of calorie labeling on fast-food purchases is unclear. McDonald’s voluntarily labeled its menus with calories in 2012, providing an opportunity to evaluate this initiative on purchases.

    Joshua Petimar, Maricelle Ramirez in International Journal of Behavioral Nutrit… (2019)

  17. Article

    Open Access

    The nasal methylome as a biomarker of asthma and airway inflammation in children

    The nasal cellular epigenome may serve as biomarker of airway disease and environmental response. Here we collect nasal swabs from the anterior nares of 547 children (mean-age 12.9 y), and measure DNA methylat...

    Andres Cardenas, Joanne E. Sordillo, Sheryl L. Rifas-Shiman in Nature Communications (2019)

  18. Article

    Correction: Maternal obesity and offspring cognition: the role of inflammation

    Following publication of this article, the authors noted that the name of the last author was incorrectly displayed as ‘Sen Sarbattama’. This authors name has now been corrected to ‘Sarbattama Sen’. This has b...

    Carmen Monthé-Drèze, Sheryl L. Rifas-Shiman, Diane R. Gold in Pediatric Research (2019)

  19. Article

    Open Access

    Prenatal maternal antidepressants, anxiety, and depression and offspring DNA methylation: epigenome-wide associations at birth and persistence into early childhood

    Maternal mood disorders and their treatment during pregnancy may have effects on the offspring epigenome. We aim to evaluate associations of maternal prenatal antidepressant use, anxiety, and depression with c...

    Andres Cardenas, Sabrina Faleschini, Andrea Cortes Hidalgo in Clinical Epigenetics (2019)

  20. Article

    Open Access

    Dietary behaviors throughout childhood are associated with adiposity and estimated insulin resistance in early adolescence: a longitudinal study

    Despite the growing prevalence of excess weight and prediabetes in children, the contributing role of dietary behaviors throughout childhood remains poorly understood. We examined longitudinal associations of ...

    Véronique Gingras, Sheryl L. Rifas-Shiman in International Journal of Behavioral Nutrit… (2018)

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