4 Result(s)
within
Sheryl L. Rifas-Shiman
Science, Humanities and Social Sciences, multidisciplinary
English
-
Article
Open AccessDNA methylation architecture of the ACE2 gene in nasal cells of children
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has led to the global coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2 enters cells via angiotensin-Converting Enzyme 2 (ACE2) receptors, hi...
-
Article
Open AccessThe nasal methylome as a biomarker of asthma and airway inflammation in children
The nasal cellular epigenome may serve as biomarker of airway disease and environmental response. Here we collect nasal swabs from the anterior nares of 547 children (mean-age 12.9 y), and measure DNA methylat...
-
Article
Open AccessRelation of Prenatal Air Pollutant and Nutritional Exposures with Biomarkers of Allergic Disease in Adolescence
Prenatal exposures may be critical for immune system development, with consequences for allergic disease susceptibility. We examined associations of prenatal exposures (nutrient intakes and air pollutants) wit...
-
Article
Open AccessPersistent DNA methylation changes associated with prenatal mercury exposure and cognitive performance during childhood
Prenatal exposure to mercury, a known neurotoxic metal, is associated with lower cognitive performance during childhood. Disruption of fetal epigenetic programming could explain mercury’s neurodevelopmental ef...
