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  1. Article

    Open Access

    YOD1 protects against MRSA sepsis-induced DIC through Lys33-linked deubiquitination of NLRP3

    Disseminated intravascular coagulation (DIC) is considered to be the most common and lethal complication of sepsis. NLR-family pyrin domain-containing-3 (NLRP3) inflammasome plays an important role in host def...

    Chang Liu, Caihong Fan, Jia Liu, Shiqi Zhang, Huixin Tang… in Cell Death & Disease (2024)

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    Article

    Syringaresinol protects against diabetic nephropathy by inhibiting pyroptosis via NRF2-mediated antioxidant pathway

    Diabetic nephropathy (DN) is one of the serious complications of diabetes that has limited treatment options. As a lytic inflammatory cell death, pyroptosis plays an important role in the pathogenesis of DN. S...

    Guangru Li, Chang Liu, Lei Yang, Lifeng Feng… in Cell Biology and Toxicology (2023)