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  1. No Access

    Article

    Treatment of Syringomyelia Characterized by Focal Dilatation of the Central Canal Using Mesenchymal Stem Cells and Neural Stem Cells

    Syringomyelia is a progressive chronic disease that leads to nerve pain, sensory dissociation, and dyskinesia. Symptoms often do not improve after surgery. Stem cells have been widely explored for the treatmen...

    Mo Li, **nyu Wang, Boling Qi, Shengyu Cui… in Tissue Engineering and Regenerative Medici… (2024)

  2. Article

    Open Access

    UGCG modulates heart hypertrophy through B4GalT5-mediated mitochondrial oxidative stress and the ERK signaling pathway

    Mechanical pressure overload and other stimuli often contribute to heart hypertrophy, a significant factor in the induction of heart failure. The UDP-glucose ceramide glycosyltransferase (UGCG) enzyme plays a ...

    Shengyu Cui, Xutao Zhang, Yuhua Li, Shan Hu… in Cellular & Molecular Biology Letters (2023)

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  3. No Access

    Article

    Upregulation of P2Y12 inhibits chondrocyte apoptosis in lumbar osteoarthritis through the PI3K/AKT signaling pathway

    Lumbar facet osteoarthritis (FJOA) is a major cause of severe lower back pain and disability worldwide. However, the mechanism underlying cartilage degeneration in FJOA remains unclear. The purpose of this stu...

    Guanyin Wu, Pengfei Xue, Huricha **, Mo Zhang, Chao Gui… in Molecular Biology Reports (2022)

  4. No Access

    Article

    MMP-1 overexpression induced by IL-1β: possible mechanism for inflammation in degenerative lumbar facet joint

    More and more attention has been focused on the inflammation or degeneration caused by biochemical factors in radiculopathy during lumbar facet joint degeneration. This study was designed to examine the expres...

    Dawei Xu, Yuyu Sun, Guofeng Bao, Wei Liu, **nhui Zhu… in Journal of Orthopaedic Science (2013)