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1,118 Result(s)
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Article
Decline in atmospheric nitrogen deposition in China between 2010 and 2020
The deposition of atmospheric nitrogen sourced from emissions has broad environmental consequences, but long-term measurements of recent air pollution control and nitrogen management effectiveness in China are...
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Benefits of Hepatitis C Viral Eradication: A Real-World Nationwide Cohort Study in Taiwan
Chronic hepatitis C (CHC) increases the risk of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). This nationwide cohort study assessed the effectiveness of viral eradication of CHC.
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Article
A correlated ferromagnetic polar metal by design
Polar metals have recently garnered increasing interest because of their promising functionalities. Here we report the experimental realization of an intrinsic coexisting ferromagnetism, polar distortion and m...
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Article
Open AccessVascular endothelial dysfunction induced by 3-bromofluoranthene via MAPK-mediated-NFκB pro-inflammatory pathway and intracellular ROS generation
3-Bromofluoranthene (3-BrFlu) is the secondary metabolite of fluoranthene, which is classified as a polycyclic aromatic hydrocarbon, through bromination and exists in the fine particulate matter of air polluta...
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Spatiotemporal Variability and Environmental Controls of Temperature Sensitivity of Ecosystem Respiration across the Tibetan Plateau
Warming-induced carbon loss via ecosystem respiration (Re) is probably intensifying in the alpine grassland ecosystem of the Tibetan Plateau owing to more accelerated warming and the higher temperature sensitivit...
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Article
Identification method for design parameters of single-action tapered spool restrictors
The performances of a hydrostatic bearing using the tapered-spool restrictors with appropriate design parameters is superior to other types of pressure compensation, that is the largest stiffness obtained unde...
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Article
Response Mechanism of Dynamic Tensile Mechanics in Granite Under Microwave Irradiation: Insights from Experiments and Simulations
Microwave-assisted mechanical rock-breaking can effectively solve the problems of low efficiency of hard rock-breaking and severe wear and tear of equipment. This study used granite as the research object and ...
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Develo** Estimation Equations for the Cerchar Abrasivity Index of Rocks Applicable to TBM Tunnels
Rock abrasivity plays an important role in the machine design, construction scheduling, and budgeting of TBM projects. Establishing several faster and simpler estimation equations for the Cerchar Abrasivity In...
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Open AccessIdentification of lipid-modifying drug targets for autoimmune diseases: insights from drug target mendelian randomization
A growing body of evidence has highlighted the interactions of lipids metabolism and immune regulation. Nevertheless, there is still a lack of evidence regarding the causality between lipids and autoimmune dis...
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Article
Open AccessCholesterol efflux from C1QB-expressing macrophages is associated with resistance to chimeric antigen receptor T cell therapy in primary refractory diffuse large B cell lymphoma
Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated promising efficacy in early trials for relapsed/refractory diffuse large B cell lymphoma (DLBCL). However, its efficacy in treating primary ref...
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Article
Open AccessDistinct characteristics of the gut virome in patients with osteoarthritis and gouty arthritis
The gut microbiota and its metabolites play crucial roles in pathogenesis of arthritis, highlighting gut microbiota as a promising avenue for modulating autoimmunity. However, the characterization of the gut v...
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Open AccessDe novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation
The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...
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Binder-induced ultrafast PF6−-intercalation toward a high-voltage, high-power and long-cycling zinc–graphite dual-ion battery
Metallic zinc is an ideal anode material owing to its high theoretical capacity (819 mAh·g−1), eco-friendliness, low cost and high safety, which have driven fast development of Zn-ion batteries (ZIBs). However, t...
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HRDC challenge: a public benchmark for hypertension and hypertensive retinopathy classification from fundus images
Hypertensive retinopathy (HR) can potentially lead to vision loss if left untreated. Early screening and treatment are critical in reducing the risk of vision loss. The computer-aided diagnostic system present...
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Open AccessAssociation between socioeconomic and motherhood characteristics with receiving community-based treatment services among justice-involved young female drug users: a retrospective cohort study in Taiwan
Drug-involved individuals who contact treatment services in Taiwan are mostly driven by criminal justice systems either as an alternative or adjunct to criminal sanctions for a drug offence. With a focus on ju...
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Unraveling the Mechanisms of Cannabidiol’s Pharmacological Actions: A Comprehensive Research Overview
Cannabis sativa has long been used for neurological and psychological healing. Recently, cannabidiol (CBD) extracted from cannabis sativa has gained prominence in the medical field due to its non-psychotropic ...
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Open AccessReal-World Efficacy and Safety of Universal 8-Week Glecaprevir/Pibrentasvir for Treatment-Naïve Patients from a Nationwide HCV Registry in Taiwan
Eight-week glecaprevir/pibrentasvir (GLE/PIB) is indicated for treatment-naïve (TN) patients with chronic hepatitis C (CHC), with or without compensated cirrhosis. Given that the Taiwanese government is commit...
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Digital Twin-Based Pump Station Dynamic Scheduling for Energy-Saving Optimization in Water Supply System
In urban water supply systems, pump stations are the hubs for making the complete systems operate regularly as well as the main energy-consuming units. In order to address the current problems of water supply ...
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Article
AI-enhanced digital technologies for myopia management: advancements, challenges, and future prospects
Myopia, a prevalent refractive error leading to visual impairment, presents a substantial global health challenge. Current preventive measures, including pharmaceutical interventions and optical corrections, r...
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Article
H2S Regulates the Phenotypic Transformation of Astrocytes Following Cerebral Ischemia/Reperfusion via Inhibiting the RhoA/ROCK Pathway
The role of hydrogen sulfide (H2S) on the phenotypic change of astrocytes following cerebral ischemia/reperfusion (I/R) in mice was investigated in present study. We tested the expression of glial fibrillary acid...