13 Result(s)

Article

Correction: MicroRNA-765 is upregulated in myelodysplastic syndromes and induces apoptosis via PLP2 inhibition in leukemia cells

Seong-Ho Kang, Ji Seon Choi in Blood Research (2024)

Article

Real-time six-dimensional spatiotemporal tracking of single anisotropic nanoparticles in live cells by integrated multifunctional light-sheet nanoscopy

An integrated multifunctional light-sheet nanoscopy (iMLSN) combined with differential interference contrast, total internal reflection, epifluorescence, a super-resolution radial fluctuation-stream module, and a...

Yingying Cao, Seungah Lee, Kyungsoo Kim, Jong-Young Kwak… in Microchimica Acta (2023)

Article

Quantifying intracellular trafficking of silica-coated magnetic nanoparticles in live single cells by site-specific direct stochastic optical reconstruction microscopy

Nanoparticles have been used for biomedical applications, including drug delivery, diagnosis, and imaging based on their unique properties derived from small size and large surface-to-volume ratio. However, co...

Suresh Kumar Chakkarapani, Tae Hwan Shin, Seungah Lee… in Journal of Nanobiotechnology (2021)

Article

Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics

Nanoparticles have been utilized in brain research and therapeutics, including imaging, diagnosis, and drug delivery, owing to their versatile properties compared to bulk materials. However, exposure to nanopa...

Tae Hwan Shin, Balachandran Manavalan, Da Yeon Lee… in Particle and Fibre Toxicology (2021)

Article

Decrease in membrane fluidity and traction force induced by silica-coated magnetic nanoparticles

Nanoparticles are being increasingly used in biomedical applications owing to their unique physical and chemical properties and small size. However, their biophysical assessment and evaluation of side-effects ...

Tae Hwan Shin, Abdurazak Aman Ketebo, Da Yeon Lee… in Journal of Nanobiotechnology (2021)

Article

Silica-coated magnetic nanoparticles induce glucose metabolic dysfunction in vitro via the generation of reactive oxygen species

Nanoparticles are a useful material in biomedicine given their unique properties and biocompatibility; however, there is increasing concern regarding the potential toxicity of nanoparticles with respect to cel...

Tae Hwan Shin, Chan Seo, Da Yeon Lee, Moongi Ji… in Archives of Toxicology (2019)

Article

Quality and freshness of human bone marrow-derived mesenchymal stem cells decrease over time after trypsinization and storage in phosphate-buffered saline

Human bone marrow-derived mesenchymal stem cells (hBM-MSCs) have been studied for their therapeutic potential. However, evaluating the quality of hBM-MSCs before transplantation remains a challenge. We address...

Tae Hwan Shin, Seungah Lee, Ki Ryung Choi, Da Yeon Lee, Yongman Kim… in Scientific Reports (2017)

Article

Augmented 3D super-resolution of fluorescence-free nanoparticles using enhanced dark-field illumination based on wavelength-modulation and a least-cubic algorithm

Augmented three-dimensional (3D) subdiffraction-limited resolution of fluorescence-free single-nanoparticles was achieved with wavelength-dependent enhanced dark-field (EDF) illumination and a least-cubic algo...

Peng Zhang, Kyungsoo Kim, Seungah Lee, Suresh Kumar Chakkarapani… in Scientific Reports (2016)

Article

Silica-coated magnetic nanoparticles impair proteasome activity and increase the formation of cytoplasmic inclusion bodies in vitro

The potential toxicity of nanoparticles, particularly to neurons, is a major concern. In this study, we assessed the cytotoxicity of silica-coated magnetic nanoparticles containing rhodamine B isothiocyanate d...

Geetika Phukan, Tae Hwan Shin, Jeom Soon Shim, Man Jeong Paik… in Scientific Reports (2016)

Article

In vitro generation of allo-reactive human NK cells from umblillical cord blood CD34+ progenitor cells

Yong-Oon Ahn, Ha-Ram Park, Seong-Ho Kang… in Journal for ImmunoTherapy of Cancer (2015)

Article

Super-resolution of fluorescence-free plasmonic nanoparticles using enhanced dark-field illumination based on wavelength-modulation

Super-resolution imaging of fluorescence-free plasmonic nanoparticles (NPs) was achieved using enhanced dark-field (EDF) illumination based on wavelength-modulation. Indistinguishable adjacent EDF images of 10...

Peng Zhang, Seungah Lee, Hyunung Yu, Ning Fang, Seong Ho Kang in Scientific Reports (2015)

Article

Modulation of protective immunity against herpes simplex virus via mucosal genetic co-transfer of DNA vaccine with β₂-adrenergic agonist

Cholera toxin, which has been frequently used as mucosal adjuvant, leads to an irreversible activation of adenylyl cyclase, thereby accumulating cAMP in target cells. Here, it was assumed that β₂-adrenergic agoni...

Seong Bum Kim, Young Woo Han, MM Rahman, Seon Ju Kim… in Experimental & Molecular Medicine (2009)

Article

Polarization of protective immunity induced by replication-incompetent adenovirus expressing glycoproteins of pseudorabies virus

Replication-incompetent adenoviruses expressing three major glycoproteins (gB, gC, and gD) of pseudorabies virus (PrV) were constructed and used to examine the ability of these glycoproteins to induce protecti...

Young Woo Han, Abi G Aleyas, Junu A George… in Experimental & Molecular Medicine (2008)