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  1. Article

    Open Access

    Real-time six-dimensional spatiotemporal tracking of single anisotropic nanoparticles in live cells by integrated multifunctional light-sheet nanoscopy

    An integrated multifunctional light-sheet nanoscopy (iMLSN) combined with differential interference contrast, total internal reflection, epifluorescence, a super-resolution radial fluctuation-stream module, and a...

    Yingying Cao, Seungah Lee, Kyungsoo Kim, Jong-Young Kwak in Microchimica Acta (2023)

  2. Article

    Open Access

    Quantifying intracellular trafficking of silica-coated magnetic nanoparticles in live single cells by site-specific direct stochastic optical reconstruction microscopy

    Nanoparticles have been used for biomedical applications, including drug delivery, diagnosis, and imaging based on their unique properties derived from small size and large surface-to-volume ratio. However, co...

    Suresh Kumar Chakkarapani, Tae Hwan Shin, Seungah Lee in Journal of Nanobiotechnology (2021)

  3. Article

    Open Access

    Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics

    Nanoparticles have been utilized in brain research and therapeutics, including imaging, diagnosis, and drug delivery, owing to their versatile properties compared to bulk materials. However, exposure to nanopa...

    Tae Hwan Shin, Balachandran Manavalan, Da Yeon Lee in Particle and Fibre Toxicology (2021)

  4. Article

    Open Access

    Decrease in membrane fluidity and traction force induced by silica-coated magnetic nanoparticles

    Nanoparticles are being increasingly used in biomedical applications owing to their unique physical and chemical properties and small size. However, their biophysical assessment and evaluation of side-effects ...

    Tae Hwan Shin, Abdurazak Aman Ketebo, Da Yeon Lee in Journal of Nanobiotechnology (2021)