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  1. Article

    Open Access

    Real-time six-dimensional spatiotemporal tracking of single anisotropic nanoparticles in live cells by integrated multifunctional light-sheet nanoscopy

    An integrated multifunctional light-sheet nanoscopy (iMLSN) combined with differential interference contrast, total internal reflection, epifluorescence, a super-resolution radial fluctuation-stream module, and a...

    Yingying Cao, Seungah Lee, Kyungsoo Kim, Jong-Young Kwak in Microchimica Acta (2023)

  2. Article

    Open Access

    Quantifying intracellular trafficking of silica-coated magnetic nanoparticles in live single cells by site-specific direct stochastic optical reconstruction microscopy

    Nanoparticles have been used for biomedical applications, including drug delivery, diagnosis, and imaging based on their unique properties derived from small size and large surface-to-volume ratio. However, co...

    Suresh Kumar Chakkarapani, Tae Hwan Shin, Seungah Lee in Journal of Nanobiotechnology (2021)

  3. Article

    Open Access

    Decrease in membrane fluidity and traction force induced by silica-coated magnetic nanoparticles

    Nanoparticles are being increasingly used in biomedical applications owing to their unique physical and chemical properties and small size. However, their biophysical assessment and evaluation of side-effects ...

    Tae Hwan Shin, Abdurazak Aman Ketebo, Da Yeon Lee in Journal of Nanobiotechnology (2021)

  4. No Access

    Article

    3D super-localization of intracellular organelle contacts at live single cell by dual-wavelength synchronized fluorescence-free imaging

    A fluorescence-free real-time three-dimensional (3D) super-localization method for the analysis of 3D structure of organelles (e.g., mitochondria-associated endoplasm reticulum [mito-ER] contacts) in live sing...

    Suresh Kumar Chakkarapani, Peng Zhang in Analytical and Bioanalytical Chemistry (2018)

  5. No Access

    Article

    Quantification of UV-induced cyclobutane pyrimidine dimers using an oligonucleotide chip assay

    A lesion-specific enzyme-induced DNA strand break assay was developed for an oligonucleotide chip for the determination of UVB-induced cyclobutane pyrimidine dimers (CPDs). A 20-mer of fluorophore-labeled and ...

    Min Jung Kim, Su Chul Lee, Seong Ho Kang in Analytical and Bioanalytical Chemistry (2010)

  6. No Access

    Article

    Detection of single-molecule DNA hybridization by using dual-color total internal reflection fluorescence microscopy

    We examined the use of prism-type simultaneous dual-color total internal reflection fluorescence microscopy (TIRFM) to probe DNA molecules at the single-molecule level. The system allowed the direct detection ...

    Seong Ho Kang, Yun-Jeong Kim, Edward S. Yeung in Analytical and Bioanalytical Chemistry (2007)