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  1. Article

    Open Access

    The novel hsa-miR-12528 regulates tumourigenesis and metastasis through hypo-phosphorylation of AKT cascade by targeting IGF-1R in human lung cancer

    Lung cancer cases are increasing yearly; however, few novel therapeutic strategies for treating this disease have been developed. Here the dysregulation between microRNAs and oncogenes or tumour-suppressor gen...

    Seong Ho Jeon, Jung Ki Yoo, Chang Min Kim, Eun Su Lim, So Jeong Lee… in Cell Death & Disease (2018)

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  2. No Access

    Article

    Enhanced cytotoxicity of 5-FU by bFGF through up-regulation of uridine phosphorylase 1

    Anti cancer agent 5-FU (Fluoro Uracil) is a prodrug that can be metabolized and then activated to interfere with RNA and DNA homeostasis. However, the majority of administered 5-FU is known to be catabolized in v...

    Young-Sam Im, Hea Kyeong Shin, Hye-Ryun Kim, So-Hee Jeong… in Molecules and Cells (2009)