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Article
Open AccessCryo-EM structures of the ATP-bound Vps4E233Q hexamer and its complex with Vta1 at near-atomic resolution
The cellular ESCRT-III (endosomal sorting complex required for transport-III) and Vps4 (vacuolar protein sorting 4) comprise a common machinery that mediates a variety of membrane remodelling events. Vps4 is e...
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Article
Structure of phycobilisome from the red alga Griffithsia pacifica
Life on Earth depends on photosynthesis for its conversion of solar energy to chemical energy. Photosynthetic organisms have developed a variety of light-harvesting systems to capture sunlight. The largest lig...
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Article
Structural basis of energy transfer in Porphyridium purpureum phycobilisome
Photosynthetic organisms have developed various light-harvesting systems to adapt to their environments1. Phycobilisomes are large light-harvesting protein complexes found in cyanobacteria and red algae2–4, altho...
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Article
Open AccessStructural basis for energy transfer in a huge diatom PSI-FCPI supercomplex
Diatom is an important group of marine algae and contributes to around 20% of the global photosynthetic carbon fixation. Photosystem I (PSI) of diatoms is associated with a large number of fucoxanthin-chloroph...
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Article
Open AccessStructural insights into PA3488-mediated inactivation of Pseudomonas aeruginosa PldA
PldA, a phospholipase D (PLD) effector, catalyzes hydrolysis of the phosphodiester bonds of glycerophospholipids—the main component of cell membranes—and assists the invasion of the opportunistic pathogen Pseudom...
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Article
Open AccessStructure of the Acidobacteria homodimeric reaction center bound with cytochrome c
Photosynthesis converts light energy to chemical energy to fuel life on earth. Light energy is harvested by antenna pigments and transferred to reaction centers (RCs) to drive the electron transfer (ET) reacti...
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Article
Open AccessDetermining protein structures in cellular lamella at pseudo-atomic resolution by GisSPA
Cryo-electron tomography is a major tool used to study the structure of protein complexes in situ. However, the throughput of tilt-series image data collection is still quite low. Here, we show that GisSPA, a ...
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Article
In situ structure of the red algal phycobilisome–PSII–PSI–LHC megacomplex
In oxygenic photosynthetic organisms, light energy is captured by antenna systems and transferred to photosystem II (PSII) and photosystem I (PSI) to drive photosynthesis1,2. The antenna systems of red algae cons...
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Article
Nuclear export of pre-60S particles through the nuclear pore complex
The nuclear pore complex (NPC) is the bidirectional gate that mediates the exchange of macromolecules or their assemblies between nucleus and cytoplasm1–3. The assembly intermediates of the ribosomal subunits, pr...
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Article
Open AccessAuthor Correction: Determining protein structures in cellular lamella at pseudo-atomic resolution by GisSPA