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Article
Open AccessThe ion channel TRPA1 is a modulator of the cocaine reward circuit in the nucleus accumbens
Drug addiction therapies commonly fail because continued drug use promotes the release of excessive and pleasurable dopamine levels. Because the connection between pleasure and drug use becomes hard-wired in t...
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Article
Open AccessOptimal timing for the first cystoscopic follow-up using time-to-treatment initiation analysis of oncologic outcomes in primary non-muscle invasive bladder cancer
Various guidelines recommend the first follow-up cystoscopy at 3 months; however, no data exist on the optimal timing for initial follow-up cystoscopy. We tried to provide evidence on the timing of the first c...
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Article
Open AccessAvailability of ChatGPT to provide medical information for patients with kidney cancer
ChatGPT is an advanced natural language processing technology that closely resembles human language. We evaluated whether ChatGPT could help patients understand kidney cancer and replace consultations with uro...
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Article
Open AccessPersistent enhancement of basolateral amygdala-dorsomedial striatum synapses causes compulsive-like behaviors in mice
Compulsive behaviors are observed in a range of psychiatric disorders, however the neural substrates underlying the behaviors are not clearly defined. Here we show that the basolateral amygdala-dorsomedial str...
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Article
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance
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Article
Enhanced Antitumor Effect of the Combination of Bacille Calmette-Guérin and an Immune Checkpoint Inhibitor in Bladder Cancer-On-a-Chip
We upgraded preexisting bladder cancer-on-a-chip (BCOC) by adding T cells and evaluated the antitumor effect of a combination of intravesical Bacille Calmette-Guérin (BCG) and pembrolizumab. We fabricated biop...
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Article
Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance
Social hierarchy is established as an outcome of individual social behaviors, such as dominance behavior during long-term interactions with others. Astrocytes are implicated in optimizing the balance between e...
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Article
Open AccessUrinary tract infection after radiation therapy or radical prostatectomy on the prognosis of patients with prostate cancer: a population-based study
We aimed to assess the trends in urinary tract infections (UTIs) and prognosis of patients with prostate cancer after radical prostatectomy (RP) and radiation therapy (RT) as definitive treatment options.
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Article
Open AccessGemcitabine–cisplatin versus MVAC chemotherapy for urothelial carcinoma: a nationwide cohort study
This study assessed the trends in methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) and gemcitabine–cisplatin (GC) regimens in Korean patients with metastatic urothelial carcinoma (UC) and compared ...
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Article
Open AccessNeoadjuvant versus adjuvant chemotherapy in upper tract urothelial carcinoma: A nationwide cohort study
This study aimed to evaluate the trend of adjuvant chemotherapy (AC) and neoadjuvant chemotherapy (NAC) in patients who underwent radical nephroureterectomy with bladder cuff excision (NUx) for upper tract uro...
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Article
Neoadjuvant versus adjuvant chemotherapy in bladder cancer: a nationwide cohort study
Radical cystectomy is the standard of care for muscle-invasive bladder cancer. However, the 5-year survival rate is only about 50%. Therefore, additional treatments are needed. We compared the perioperative ou...
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Article
Production of human spinal-cord organoids recapitulating neural-tube morphogenesis
Human spinal-cord-like tissues induced from human pluripotent stem cells are typically insufficiently mature and do not mimic the morphological features of neurulation. Here, we report a three-dimensional cult...
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Article
Open AccessSALM4 negatively regulates NMDA receptor function and fear memory consolidation
Many synaptic adhesion molecules positively regulate synapse development and function, but relatively little is known about negative regulation. SALM4/Lrfn3 (synaptic adhesion-like molecule 4/leucine rich repe...
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Article
Open AccessCorrection to: Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors
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Article
Open AccessHybrid ileal pouch with concomitant anti-refluxing and refluxing ureteroileal anastomosis
We report our preliminary experience of using a hybrid ileal pouch, assessing oncologic outcomes, complications, voiding, and renal function.
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Article
Open AccessAltered presynaptic function and number of mitochondria in the medial prefrontal cortex of adult Cyfip2 heterozygous mice
Variants of the cytoplasmic FMR1-interacting protein (CYFIP) gene family, CYFIP1 and CYFIP2, are associated with numerous neurodevelopmental and neuropsychiatric disorders. According to several studies, CYFIP1 re...
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Article
Survival strategy of urology department during the COVID-19 era
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Article
Open AccessReceptor protein tyrosine phosphatase delta is not essential for synapse maintenance or transmission at hippocampal synapses
Members of the leukocyte common antigen-related receptor protein tyrosine phosphatase (LAR-RPTP) family, comprising PTPσ, PTPδ and LAR, are key hubs for presynaptic assembly and differentiation in vertebrate n...
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Article
Percent tumor volume vs American Joint Committee on Cancer staging system subclassification for predicting biochemical recurrence in patients with pathologic T2 prostate cancer
Here, we re-checked the American Joint Committee on Cancer 7th edition subclassification and confirmed the possibility of percent tumor volume as a prognostic factor for biochemical recurrence in the 8th editi...
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Surgical Consideration in Renal Tumors
This chapter addresses the surgical management of localized, locally advanced, and metastatic renal cell carcinoma. Multiple management options are available for clinical T1 renal mass. Partial nephrectomy is ...
