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  1. Article

    Reconciling stochastic origin firing with defined replication timing

    Eukaryotic chromosomes replicate with defined timing patterns. However, the mechanism that regulates the timing of replication is unknown. In particular, there is an apparent conflict between population experi...

    Nicholas Rhind, Scott Cheng-Hsin Yang, John Bechhoefer in Chromosome Research (2010)

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    Computational Methods to Study Kinetics of DNA Replication

    New technologies such as DNA combing have led to the availability of large quantities of data that describe the state of DNA while undergoing replication in S phase. In this chapter, we describe methods used t...

    Scott Cheng-Hsin Yang, Michel G. Gauthier, John Bechhoefer in DNA Replication (2009)