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  1. No Access

    Article

    Population Pharmacokinetics of Levetiracetam in Patients with Traumatic Brain Injury and Subarachnoid Hemorrhage Exhibiting Augmented Renal Clearance

    Patients with severe trauma exhibit augmented renal clearance, which can alter the dosing requirement of renally eliminated drugs. This study aimed to develop a population pharmacokinetic model for levetiracet...

    Fekade Bruck Sime, Jason A. Roberts, Rosalind L. Jeffree… in Clinical Pharmacokinetics (2021)

  2. Article

    Open Access

    Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients

    The population pharmacokinetics of total and unbound posaconazole following intravenous administration has not yet been described for the critically ill patient population. The aim of this work was, therefore,...

    Fekade B. Sime, Catherine J. Byrne, Suzanne Parker, Janine Stuart… in Critical Care (2019)

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