4 Result(s)
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Article
Open AccessThe effect of prolonged of warm ischaemic injury on renal function in an experimental ex vivo normothermic perfusion system
Donation after circulatory death (DCD) kidney transplants inevitably sustain a degree of warm ischaemic injury, which is manifested clinically as delayed graft function. The aim of this study was to define the...
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Article
Open AccessThe use of ex-vivo normothermic perfusion for the resuscitation and assessment of human kidneys discarded because of inadequate in situ perfusion
Many kidneys are rejected for transplantation due to inadequate in situ perfusion during organ retrieval because of the risk of additional ischaemic injury and microvasculature thrombosis. This study describes...
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Article
Open AccessHaemoadsorption reduces the inflammatory response and improves blood flow during ex vivo renal perfusion in an experimental model
Ex-vivo normothermic perfusion strategies are a promising new instrument in organ transplantation. The perfusion conditions are designed to be protective however the artificial environment can induce a local i...
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Article
Open AccessNormothermic machine perfusion versus static cold storage in donation after circulatory death kidney transplantation: a randomized controlled trial
Kidney transplantation is the optimal treatment for end-stage renal disease, but it is still severely limited by a lack of suitable organ donors. Kidneys from donation after circulatory death (DCD) donors have...
