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Open AccessCorrection: characteristics of insulin resistance in Korean adults from the perspective of circadian and metabolic sensing genes
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Open AccessCharacteristics of insulin resistance in Korean adults from the perspective of circadian and metabolic sensing genes
The biological clock allows an organism to anticipate periodic environmental changes and adjust its physiology and behavior accordingly.
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Article
Open AccessSynergistic effect of YOD1 and USP21 on the Hippo signaling pathway
Deubiquitinating enzymes (DUBs) comprise a family of proteases responsible for cleaving the peptide or isopeptide bond between ubiquitin and its substrate proteins. Ubiquitin is essential for regulating divers...
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Article
Open AccessRamifications of POU4F3 variants associated with autosomal dominant hearing loss in various molecular aspects
POU4F3, a member of the POU family of transcription factors, commonly causes autosomal dominant deafness. Exome sequencing was used to identify four novel variants in POU4F3 (NM_002700.2), including c.564dupA: p....
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Article
Open AccessTargeting β-catenin overcomes MEK inhibition resistance in colon cancer with KRAS and PIK3CA mutations
Mitogen-activated protein kinases (MEK 1/2) are central components of the RAS signalling pathway and are attractive targets for cancer therapy. These agents continue to be investigated in KRAS mutant colon cancer...