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  1. Article

    Open Access

    Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies

    Activation of platelet-derived growth factor receptor alpha (PDGFRA) by genomic aberrations contributes to tumor progression in several tumor types. In this study, we characterize 16 novel PDGFRA mutations identi...

    Carman K. M. Ip, Patrick K. S. Ng, Kang ** Jeong, S. H. Shao… in Nature Communications (2018)

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  2. Article

    A dynamic model for the p53 stress response networks under ion radiation

    P53 controls the cell cycle arrest and cell apoptosis through interaction with the downstream genes and their signal pathways. To stimulate the investigation into the complicated responses of p53 under the cir...

    J.-P. Qi, S.-H. Shao, D.-D. Li, G.-P. Zhou in Amino Acids (2007)

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