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  1. Article

    Preparation of 2-Isopropylthiamo rpholin-3-one-5-carboxylic Acid

    ISOVALTHINE is a new sulphur-containing amino-acid which is isolated from the urine of hypercholesterolæmic patients1,2. A molecular model of isovalthine suggests a possibility of forming a thiamorpholinone deriv...

    S. MIZUHARA, S. OHMORI, K. HORIUCHI, T. KUWAKI, T. UBUKA in Nature (1963)

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    Article

    Configuration of Urinary Isovalthine

    ISOVALTHINE crystals first isolated from urine were rhombic plates which gave DL-alanine after treatment with Raney nickel. Needle-shaped crystals were obtained by condensation of L-cysteine and (±)-α-bromoisoval...

    S. OHMORI, T. UBUKA, T. KUWAKI, K. HORIUCHI, S. MIZUHARA in Nature (1963)