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  1. No Access

    Article

    Kaolin-induced writhing in mice, a new model of possible bradykinin-induced pain for assessment of analgesic agents

    Kaolin induced a clear and reproducible writhing reaction when intraperitoneally injected into mice. A simultaneous injection (i.p.) of soybean trypsin inhibitor (SBTI) significantly suppressed the kaolininduc...

    T. Fujiyoshi, I. Hayashi, S. Oh-ishi, M. Kuwashima, H. Iida, M. Dozen… in Agents and Actions (1989)

  2. No Access

    Article

    Roles of kallikrein-kinin system in acute inflammation: Studies on high- and low-molecular weight kininogens-deficient rats (B/N-Katholiek strain)

    Carrageenin-induced paw edema in HMW- and LMW-kininogens-deficient rats was significantly less than that in normal rats. There are three kiniogens, HMW-, LMW- and T-kininogens, in normal rat plasma, but B/N-Ka...

    S. Oh-ishi, I. Hayashi, I. Utsunomiya, M. Hayashi, K. Yamaki… in Agents and Actions (1987)