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Open AccessThe effects of high-fat feeding on physical function and skeletal muscle extracellular matrix
Skeletal muscle extracellular matrix (ECM) remodelling has been proposed as a feature of the pathogenic milieu associated with obesity and metabolic dysfunction. Whether muscle ECM is associated with impaired ...
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Article
A novel primate model of delayed wound healing in diabetes: dysregulation of connective tissue growth factor
Chronic non-healing wounds are a common complication of diabetes. Prolonged inflammation and decreased matrix accumulation may contribute. Connective tissue growth factor (CTGF) is induced during normal wound ...
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Article
Mitochondrial DNA content in peripheral blood monocytes: relationship with age of diabetes onsetand diabetic complications
We examined whether age of type 2 diabetes onset is related to mitochondrial DNA content in peripheral blood monocytes (PBMCs).
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Article
Alterations in liver sinusoidal endothelium in a baboon model of type 1 diabetes
Diabetes mellitus is associated with extensive vascular pathology, yet little is known about its long-term effects on liver sinusoidal endothelial cells (LSECs). Potential diabetic changes in LSECs are importa...
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Article
The time has come to target connective tissue growth factor in diabetic complications