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Unrelated cord blood transplantation in aplastic anemia: is anti-thymocyte globulin indispensable for conditioning?
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Article
Genomic determinants of chronic myelomonocytic leukemia
The biology, clinical phenotype and progression rate of chronic myelomonocytic leukemia (CMML) are highly variable due to diverse initiating and secondary clonal genetic events. To determine the effects of mol...
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Article
Recurrent MYB rearrangement in blastic plasmacytoid dendritic cell neoplasm
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Germline IKAROS mutation associated with primary immunodeficiency that progressed to T-cell acute lymphoblastic leukemia
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Article
Second allogeneic hematopoietic stem cell transplantation in children with severe aplastic anemia
The outcome of 55 children with severe aplastic anemia (SAA) who received a second hematopoietic stem cell transplantation (HSCT) was retrospectively analyzed using the registration data of the Japanese Societ...
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Long-term outcome of childhood aplastic anemia patients who underwent allogeneic hematopoietic SCT from an HLA-matched sibling donor in Japan
We report long-term outcomes of 329 childhood severe aplastic anemia (SAA) patients who underwent hematopoietic SCT (HSCT) from an HLA-matched sibling donor in the Japanese Hematopoietic Cell Transplantation R...
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Article
Response to the article by Linnankivi et al., entitled ‘Cerebroretinal microangiopathy with calcifications and cyst, Revesz syndrome and aplastic anemia’
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Article
Posterior reversible encephalopathy syndrome in a child with post-transplant HHV-6B encephalitis
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Article
Allo-SCT in a patient with CRMCC with aplastic anemia using a reduced intensity conditioning regimen
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Autoimmune-like hepatitis following unrelated BMT successfully treated with rituximab
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High incidence of fatty liver and insulin resistance in long-term adult survivors of childhood SCT
Overweight/obesity among adult survivors of childhood SCT has been considered to be predictive of eventual development of metabolic abnormalities. Fatty liver is increasingly recognized as a major cause of liv...
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Article
Bone marrow mononuclear cells versus G-CSF-mobilized peripheral blood mononuclear cells for treatment of lower limb ASO: pooled analysis for long-term prognosis
In this study, we report the comparative result of long-term clinical prognoses for patients with no-option critical limb ischemia (CLI) caused by arteriosclerosis obliterans, who are implanted with autologous...
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Article
Comparison of matched-sibling donor BMT and unrelated donor BMT in children and adolescent with acquired severe aplastic anemia
From January 1991 to March 2007, 61 children and adolescent with acquired severe aplastic anemia received BMT in our institutions. We retrospectively compared the outcome of 30 cases of matched-sibling donor B...
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Article
Relationship between tacrolimus blood concentrations and clinical outcome during the first 4 weeks after SCT in children
The relationship between tacrolimus concentration and acute GVHD is not well known, with few published data available for lower target levels. We hypothesized that lower levels of tacrolimus would correlate wi...
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Article
Late-onset non-infectious pulmonary complications following allogeneic hematopoietic stem cell transplantation in children
Late-onset non-infectious pulmonary complications (LONIPCs) that arise beyond 3 months after allogeneic hematopoietic SCT include bronchiolitis obliterans (BO), bronchiolitis obliterans with organizing pneumon...
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Article
Primary infection of human herpesvirus-6 in an infant who received cord blood SCT
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Article
Ikaros is a mutational target for lymphomagenesis in Mlh1-deficient mice
Deficiencies in DNA mismatch repair (MMR) result in replication errors within key tumor suppressor genes or oncogenes, and cause hereditary nonpolyposis colorectal cancer (HNPCC). Hematological malignancy with...
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Article
JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non-Down syndrome adults
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Effects of mitiglinide on glucose-induced insulin release into the portal vein and fat-induced triglyceride elevation in prediabetic and diabetic OLETF rats
Objective: The effect of single-dose mitiglinide on glucose and lipid metabolism was examined in OLETF rats with spontaneous type 2 diabetes in which the early insulin response following glucose challenge is k...
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Comprehensive analysis of gene alterations in acute megakaryoblastic leukemia of Down's syndrome