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  1. Article

    Hyperglycaemia is associated with changes in the regional concentrations of glucose and myo-inositol within the brain

    The aim of the study was to assess the effect of hyperglycaemia on regional concentrations of glucose and other substrates within the brain in non-diabetic individuals and in patients with type 1 diabetes.

    O. Heikkilä, N. Lundbom, M. Timonen, P.-H. Groop, S. Heikkinen… in Diabetologia (2009)

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  2. Article

    Synergistic effect of polymorphisms in uncoupling protein 1 and β3-adrenergic receptor genes on basal metabolic rate in obese Finns

    The polymorphisms in the uncoupling protein 1 (UCP1, A to G) and β 3-adrenergic receptor (β 3-AR, Trp64Arg) genes have been suggested to be associated with an increased tendency t...

    R. Valve, S. Heikkinen, A. Rissanen, M. Laakso, M. Uusitupa in Diabetologia (1998)

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  3. Article

    New variants in the glycogen synthase gene (Gln71His, Met416Val) in patients with NIDDM from eastern Finland

    Impaired glycogen synthesis after insulin stimulation accounts for most of the insulin resistance in patients with non-insulin-dependent diabetes mellitus (NIDDM). The glycogen synthase gene (GYS1), which enco...

    J. Rissanen, J. Pihlajamäki, S. Heikkinen, P. Kekäläinen, L. Mykkänen… in Diabetologia (1997)

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