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Article
A new method of assessing the efficiency of second harmonic generation by small samples of organic crystals
The intensity of optical second harmonic generation was measured from pressed KCl disks containing low concentrations (1%) of non-linear optical (NLO) materials. Comparison of the signals at 532 nm, with the k...
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Article
Proteome analysis of rainbow trout (Oncorhynchus mykiss) liver proteins during short term starvation
Basal rates of protein synthesis in the liver are similar in fed and starved trout; during starvation protein degradation must increase as the animal loses weight and the liver decreases in size. Little is kno...
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Article
Meropenem pharmacokinetics in children and adolescents receiving hemodialysis
The emergence of multi-drug-resistant bacteria is of great concern to the care of pediatric end-stage renal disease (ESRD) patients who receive either hemodialysis or peritoneal dialysis via a catheter. Infec...
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Article
Ubiquitin-proteasome-dependent proteolysis in rainbow trout (Oncorhynchus mykiss): effect of food deprivation
The ubiquitin-proteasome proteolytic pathway is a major route of protein degradation and of particular importance in muscle proteolysis in mammals. In this study, the β proteasome subunit N3 and polyubiquitin...
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Article
Efficacy and safety of rasburicase, a recombinant urate oxidase (Elitek™), in the management of malignancy-associated hyperuricemia in pediatric and adult patients: final results of a multicenter compassionate use trial
The recombinant urate oxidase, rasburicase (Elitek™, Sanofi-Synthelabo, Inc.), has recently received regulatory approval for the prevention and treatment of hyperuricemia in children with leukemia, lymphoma, a...