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    Article

    KIT-D816V oncogenic activity is controlled by the juxtamembrane docking site Y568-Y570

    Mutation of KIT receptor tyrosine kinase at residue D816 results in ligand-independent constitutive kinase activity. This mutation occurs in most patients with mastocytosis, a myeloproliferative neoplasm, and ...

    A Chaix, M-L Arcangeli, S Lopez, E Voisset, Y Yang, M Vita, S Letard… in Oncogene (2014)