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  1. No Access

    Article

    Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia

    Although TP53 mutations are rare in acute myeloid leukemia (AML), wild type p53 function is habitually annulled through overexpression of MDM2 or through various mechanisms including epigenetic silencing by histo...

    E McCormack, I Haaland, G Venås, R B Forthun, S Huseby, G Gausdal, S Knappskog… in Leukemia (2012)

  2. Article

    Open Access

    Cyclic AMP induces IPC leukemia cell apoptosis via CRE-and CDK-dependent Bim transcription

    The IPC-81 cell line is derived from the transplantable BNML model of acute myelogenic leukemia (AML), known to be a reliable predictor of the clinical efficiency of antileukemic agents, like the first-line AM...

    S Huseby, G Gausdal, T J Keen, E Kjærland, C Krakstad, L Myhren… in Cell Death & Disease (2011)

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