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    Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia

    Although TP53 mutations are rare in acute myeloid leukemia (AML), wild type p53 function is habitually annulled through overexpression of MDM2 or through various mechanisms including epigenetic silencing by histo...

    E McCormack, I Haaland, G Venås, R B Forthun, S Huseby, G Gausdal, S Knappskog in Leukemia (2012)