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    Article

    Precise small-molecule recognition of a toxic CUG RNA repeat expansion

    Dimeric bis-benzimidazole compounds that bind selectively to toxic expanded r(CUG) RNA repeat sequences were identified and used as a scaffold for covalent modification, site-specific cleavage and on-target assem...

    Suzanne G Rzuczek, Lesley A Colgan, Yoshio Nakai… in Nature Chemical Biology (2017)