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Article
Open AccessA multi-kingdom collection of 33,804 reference genomes for the human vaginal microbiome
The human vagina harbours diverse microorganisms—bacteria, viruses and fungi—with profound implications for women’s health. Genome-level analysis of the vaginal microbiome across multiple kingdoms remains limi...
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Article
Elucidation of the last steps of photo-ammonification: analytical method development and mechanism elucidation
The mechanisms underlying the photo-ammonification of nitrogenous organic compounds (NOCs) remain unclear, partly due to the analytical challenges of small NOC intermediates. This study introduced a simple met...
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Article
Open AccessAltered gut mycobiome in patients with end-stage renal disease and its correlations with serum and fecal metabolomes
The relationship between the gut mycobiome and end-stage renal disease (ESRD) remains largely unexplored.
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Article
A GPU-accelerated simulator for the DEM analysis of granular systems composed of clump-shaped elements
This paper discusses the use of the discrete element method (DEM) to simulate the dynamics of granular systems made up of elements with nontrivial geometries. The DEM simulator is GPU accelerated and can handl...
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Chapter and Conference Paper
Harmonic Voltage Effect on Partial Discharge Characteristics of Oil-Paper Insulation Under Non-uniform Electric Field
In the new power system, the harmonic source and the content increase, which puts forward a new test to the oil-impregnated paper insulation performance of the transformer. Therefore, this paper carries out th...
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Article
Open AccessMetagenome-wide analysis uncovers gut microbial signatures and implicates taxon-specific functions in end-stage renal disease
The gut microbiota plays a crucial role in regulating host metabolism and producing uremic toxins in patients with end-stage renal disease (ESRD). Our objective is to advance toward a holistic understanding of...
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Article
Hierarchical learning with backtracking algorithm based on the Visual Confusion Label Tree for large-scale image classification
In this paper, a hierarchical learning algorithm based on the Bayesian Neural Network classifier with backtracking is proposed to support large-scale image classification, where a Visual Confusion Label Tree i...
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Article
Open AccessIs oral microbiome of children able to maintain resistance and functional stability in response to short-term interference of ingesta?
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Article
Open AccessAssociation between endometrial indoleamine 2,3-dioxygenase expression level and pregnancy outcomes in women undergoing first in vitro fertilization treatment
Indoleamine 2,3-dioxygenase (IDO) has been reported to play a key role in placental development during normal pregnancy. However, the question of whether endometrial IDO expression affects in vitro fertilizati...
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Protocol
Methods for Membranes and Other Absorbent Surfaces
Membrane arrays are a unique array platform option for the detection of multiple analytes or materials simultaneously. Their naturally absorptive properties and near universal use in various laboratory methods...
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Protocol
Global Detection of Proteins by Label-Based Antibody Array
Because of narrow availability of antibody pairs and potential cross-reactivity between antibodies, the development of sandwich-based antibody arrays which need a pair of antibodies for each target has been re...
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Protocol
Enhanced Protein Profiling Arrays for High-Throughput Quantitative Measurement of Cytokine Expression
The antibody array has become a powerful technology in recent years and is widely used to detect the expression levels of various proteins such as cytokines, growth factors, chemokines, and angiogenic factors,...
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Article
Enzymatic graft polymerization from cellulose acetoacetate: a versatile strategy for cellulose functionalization
A novel approach was developed to prepare cellulose acetoacetate-graft-copolymers via horseradish peroxidase (HRP)-mediated polymerization. Cellulose acetoacetate (CAA), the macroinitiator, was obtained by transe...
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Article
Open AccessSystematic analysis of gut microbiota in pregnant women and its correlations with individual heterogeneity
The woman’s gut microbiota during pregnancy may support nutrient acquisition, is associated with diseases, and has been linked to infant health. However, there is limited information on gut microbial character...
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Article
Open AccessAbnormal Expression of Indoleamine 2, 3-Dioxygenase in Human Recurrent Miscarriage
Indoleamine 2, 3-dioxygenase (IDO), an immunosuppressive enzyme that mediates the conversion of tryptophan to kynurenine, was shown to play a key role in placental development during normal pregnancy. However,...
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Chapter and Conference Paper
Accuracy Evaluation of Long Short Term Memory Network Based Language Model with Fixed-Point Arithmetic
Long Short Term Memory network based language models are state-of-art techniques in the field of natural language processing. Training LSTM networks is computationally intensive, which naturally results in inv...
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Article
Efficient production of enantiomerically pure d-phenyllactate from phenylpyruvate by structure-guided design of an engineered d-lactate dehydrogenase
3-Phenyllactic acid (PLA) is an antimicrobial compound with broad-spectrum activity against bacteria and fungi that could be widely used in the food industry and livestock feeds. Notably, d-PLA exhibits higher an...
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Article
Open AccessErratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer’s brain
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Article
Open AccessNetwork-driven plasma proteomics expose molecular changes in the Alzheimer’s brain
Biological pathways that significantly contribute to sporadic Alzheimer’s disease are largely unknown and cannot be observed directly. Cognitive symptoms appear only decades after the molecular disease onset, ...
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Chapter and Conference Paper
Study of Phosphorus Removal Efficiency in Enhanced Biological Phosphorus Removal Process
An enhanced biological phosphorus removal (EBPR) system was developed in sequencing batch reactor (SBR) using acetate as the carbon source. The SBR was operated for over 2 months. Excellent phosphorus removal ...
