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Article
EPSTI1 promotes monocyte adhesion to endothelial cells in vitro via upregulating VCAM-1 and ICAM-1 expression
Atherosclerosis is a chronic inflammatory disease of arterial wall, and circulating monocyte adhesion to endothelial cells is a crucial step in the pathogenesis of atherosclerosis. Epithelial-stromal interacti...
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Article
Cystine supplementation rebalances the redox homeostasis of microenvironment in non-small cell lung cancer cells and reverses their resistance to docetaxel
Continuous docetaxel (DTX) treatment of non-small cell lung cancer induces development of drug resistance, but the mechanism is poorly understood. In this study we performed metabolomics analysis to characteri...
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Article
A Facile Strategy for Non-fluorinated Intrinsic Low-k and Low-loss Dielectric Polymers: Valid Exploitation of Secondary Relaxation Behaviors
High-performance low-k and low-loss circuit materials are urgently needed in the field of microelectronics due to the upcoming Fifth-Generation Mobile Communications Technology (5G Technology). Herein, a facile d...
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Article
Open AccessCompound danshen drip** pills normalize a reprogrammed metabolism of myocardial ischemia rats to interpret its time-dependent efficacy in clinic trials: a metabolomic study
Clinical trials of Compound danshen drip** pills (CDDP) indicated distinct improvement in patients with chronic stable angina. Daily fluctuation of therapeutic effect agreed with a peak-valley PK profile dur...
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Article
Open AccessWeak decays of doubly heavy baryons: \(\mathcal{B}_{cc}\rightarrow \mathcal{B}_c V\)
The weak decays of a spin-1 / 2 doubly charm baryon ( \(\mathcal{B}_{cc}\) ...
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Article
Expression and clinical significance of STIP1 in papillary thyroid carcinoma
The aim of this study was to detect stress-induced phosphoprotein 1 (STIP1) expression in papillary thyroid carcinoma (PTC) and to analyze its association with prognosis of PTC patients. Immunohistochemistry w...
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Article
Pharmacokinetic interactions between 20(S)-ginsenoside Rh2 and the HIV protease inhibitor ritonavir in vitro and in vivo
20(S)-Ginsenoside Rh2 (Rh2) has shown potent inhibition on P-glycoprotein (P-gp), while most HIV protease inhibitors are both substrates and inhibitors of P-gp and CYP3A4. The aim of this study was to investigate...
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Article
Synthesis, structure and DNA-binding studies on the 2-(3-chlorophenyl)imidazo[4,5-f]1,10-phenanthroline-bis(2,2′-bipy ridine)-ruthenium(II) complex
A new polypyridyl ligand, MCP {MCP = 2-(3-chlorophenyl)imidazo[4,5-f]1,10-phenanthroline} and its ruthenium(II) complex, [Ru(bpy)2(MCP)](ClO4)2· 0.5MeCN (bpy = 2,2′-bipyridine), have been synthesized and chara...