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Article
Clinical study of Pai-Neng-Da capsule (派能达胶囊) in the treatment of chronic aplastic anemia
To evaluate the effificacy and safety of Pai-Neng-Da Capsule (派能达胶囊, panaxadiol saponins component, PND), a new Chinese patent medicine, on patients with chronic aplastic anemia (CAA) and to explore the optima...
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Article
Effects of panaxadiol saponins component as a new Chinese patent medicine on proliferation, differentiation and corresponding gene expression profile of megakaryocytes
To investigate the effects of panaxadiol saponins component (PDS-C) isolated from total saponins of panax ginseng on proliferation, differentiation and corresponding gene expression profile of megakaryocytes.
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Article
Effects of Danshen Injection (丹参注射液) on inhibiting proliferation and inducing apoptosis through down-regulation of mutant JAK2 gene and its protein phosphorylation in human erythroid leukemic cells
To explore the effects of Danshen Injection (丹参注射液) on inhibition proliferation, inducing apoptosis and its possible mechanisms on human erythroid leukemic (HEL) cells.
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Article
Rubus parvifolius L. inhibited the growth of leukemia K562 cells in vitro and in vivo
To determine the antiproliferative activity of Rubus parvifolius L. (RP) extract, its medicinal serum and RP total saponins (RPTS) against K562 cells in vitro and in vivo.
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Article
Effects of sodium copper chlorophyllin on mesenchymal stem cell function in aplastic anemia mice
To investigate the effects of sodium copper chlorophyllin (SCC) on the proliferation, differentiation and immunomodulatory function of mesenchymal stem cells (MSCs) from mice with aplastic anemia.
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Article
Panax notoginseng saponins induced up-regulation, phosphorylation and binding activity of MEK, ERK, AKT, PI-3K protein kinases and GATA transcription factors in hematopoietic cells
To investigate the effects of panax notoginseng saponins (PNS) on expression, regulation and phosphorylation of multiple protein kinases in mitogen activated protein kinase (MAPK) intracellular signal pathway ...
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Article
Research and development of the effective components of panaxdiol saponin as new chinese patent medicine for treating hemocytopenia
Pancytopenia (hemocytopenia) such as pr imary immune primary thrombocytopenia (ITP), aplastic anemia and chronic neutropenia (agnogenic leukocytopenia) were of ten t reated by glucocor t icoids, androgen and o...
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Article
Effects of Panax notoginseng saponins on proliferation and differentiation in NIH3T3 cells
To investigate the effects of Panax notoginseng saponins (PNS) on the proliferation and differentiation in NIH3T3 cells.
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Article
Research and development of new Chinese materia medica for treatment of refractory hematopathy by establishment and application of multiple technique platforms