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Article
Prevalence, predictors, and outcomes of acute respiratory distress syndrome in severe stroke
Patients with severe stroke are at high risk of develo** acute respiratory distress syndrome (ARDS), but this severe complication was often under-diagnosed and rarely explored in stroke patients. We aimed to...
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Article
A clinical-radiomics nomogram based on spectral CT multi-parameter images for preoperative prediction of lymph node metastasis in colorectal cancer
To develop a clinical-radiomics nomogram based on spectral CT multi-parameter images for predicting lymph node metastasis in colorectal cancer. A total of 76 patients with colorectal cancer and 156 lymph nodes...
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Article
Open AccessArnicolide D induces endoplasmic reticulum stress-mediated oncosis via ATF4 and CHOP in hepatocellular carcinoma cells
Endoplasmic reticulum (ER) stress can trigger various cell death mechanisms beyond apoptosis, providing promise in cancer treatment. Oncosis, characterized by cellular swelling and increased membrane permeabil...
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Article
Narrowband blue emitter based on fused nitrogen/carbonyl combination with external quantum efficiency approaching 30%
Multi-resonance thermally activated delayed fluorescence (MR-TADF) emitters can enable narrowband emission with high color purity and electroluminescence efficiency. Nitrogen/carbonyl (N/C=O) system is receivi...
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Article
Correlating the fluctuated growth of carbon nanotubes with catalyst evolution by atmospheric-pressure environmental transmission electron microscopy
Rate-controlled growth of carbon nanotubes (CNTs) and catalyst design are considered efficient ways for the preparation of CNTs with specific structures and properties. However, due to the difficulties in capt...
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Article
A cross-sectional quality assessment of TikTok content on benign prostatic hyperplasia
With an increasing reliance on online sources for medical information, we studied the quality and completeness of health literacy videos on TikTok regarding BPH.
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Article
Open AccessAge-related self-DNA accumulation may accelerate arthritis in rats and in human rheumatoid arthritis
The incidence of rheumatoid arthritis (RA) is increasing with age. DNA fragments is known to accumulate in certain autoimmune diseases, but the mechanistic relationship among ageing, DNA fragments and RA patho...
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Article
Mechanical and Corrosion Behavior of a Biomedical Mg–6Zn–0.5Zr Alloy Containing a Large Number of Twins
The strong texture of Mg alloys can lead to strong tension–compression yield asymmetry and corrosion anisotropy, and this will consequently affect the effectiveness of hard tissue implants. A biomedical Mg–6Zn...
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Article
Open AccessSmoking modulates different secretory subpopulations expressing SARS-CoV-2 entry genes in the nasal and bronchial airways
SARS-CoV-2 infection and disease severity are influenced by viral entry (VE) gene expression patterns in the airway epithelium. The similarities and differences of VE gene expression (ACE2, TMPRSS2, and CTSL) ...
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Article
Open AccessMifepristone combined with ethacridine lactate for third-trimester stillbirth induction: a 5-year experience from Shanghai
To review and analyze the efficacy and safety of mifepristone combined with ethacridine lactate for induction of stillbirth in the third trimester.
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Article
Open AccessSingle cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model
The use of iPSC derived brain organoid models to study neurodegenerative disease has been hampered by a lack of systems that accurately and expeditiously recapitulate pathogenesis in the context of neuron-glia...
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Article
Open AccessOn the late-time tails of massive perturbations in spherically symmetric black holes
It was first pointed out by Koyama and Tomimatsu that, under reasonable assumptions, the asymptotic late-time tails of massive scalar perturbations in the far zone of spherically symmetric black hole spacetime...
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Letter to the editor on: “The unheard parental cry of a stillbirth: fathers and mothers”
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Article
Acute posterior circulation toxic encephalopathy following wasp sting: a case report on a novel syndrome
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Article
Open AccessInactivation of the Hippo tumor suppressor pathway promotes melanoma
Melanoma is commonly driven by activating mutations in the MAP kinase BRAF; however, oncogenic BRAF alone is insufficient to promote melanomagenesis. Instead, its expression induces a transient proliferative b...
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Article
Letter to the editor on: “Never too late? Quadruplets at the age of 65 years”
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Article
Open AccessComprehensive generation, visualization, and reporting of quality control metrics for single-cell RNA sequencing data
Single-cell RNA sequencing (scRNA-seq) can be used to gain insights into cellular heterogeneity within complex tissues. However, various technical artifacts can be present in scRNA-seq data and should be asses...
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Article
Open AccessCombination of artesunate and WNT974 induces KRAS protein degradation by upregulating E3 ligase ANACP2 and β-TrCP in the ubiquitin–proteasome pathway
KRAS mutation is one of the dominant gene mutations in colorectal cancer (CRC). Up to present, targeting KRAS for CRC treatment remains a clinical challenge. WNT974 (LGK974) is a porcupine inhibitor that inter...
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Article
Clinical outcomes of individualized busulfan-dosing in hematopoietic stem cell transplantation in Chinese children undergoing with therapeutic drug monitoring
To identify relationships between busulfan (Bu) exposure and outcomes of a cohort pediatric patients receiving hematopoietic stem cell transplantation (HSCT), along with a targeted busulfan-based conditioning ...
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Article
Open AccessQuasinormal modes in two-photon autocorrelation and the geometric-optics approximation
In this work, we study the black hole light echoes in terms of the two-photon autocorrelation and explore their connection with the quasinormal modes. It is shown that the above time-domain phenomenon can be a...
