132 Result(s)

Article

Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases

Mitotic catastrophe (MC), which occurs under dysregulated mitosis, represents a fascinating tactic to specifically eradicate tumor cells. Whether pyroptosis can be a death form of MC remains unknown. Proteasom...

Zhan-Li Chen, Chen **e, Wei Zeng, Rui-Qi Huang… in Signal Transduction and Targeted Therapy (2024)

Article

Applying LASSO logistic regression for the prediction of biliary complications after ex vivo liver resection and autotransplantation in patients with end-stage hepatic alveolar echinococcosis

The purpose of this study was to explore the relevant risk factors associated with biliary complications (BCs) in patients with end-stage hepatic alveolar echinococcosis (HAE) following ex vivo liver resection...

**n Lin, Ying-Mei Shao, Rui-Qing Zhang… in European Journal of Medical Research (2024)

Article

An endothelial-related prognostic index for bladder cancer patients

Within the tumor microenvironment, endothelial cells hold substantial sway over bladder cancer (BC) prognosis. Herein, we aim to elucidate the impact of endothelial cells on BC patient outcomes by employing an...

Deng-xiong Li, Rui-cheng Wu, Jie Wang, Qing-xin Yu, Zhou-ting Tuo… in Discover Oncology (2024)

Article

A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers

Trophoblast cell surface antigen 2 (Trop2) is considered to be an attractive therapeutic target in cancer treatments. We previously generated a new humanized anti-Trop2 antibody named hIMB1636, and designated ...

Dan-dan Zhou, **ao-tian Zhai, Lan-wen Zhang, Zi-hui **e… in npj Precision Oncology (2024)

Article

Efficacy and Safety of Risankizumab in Patients with Psoriatic Arthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Currently, the cause of psoriatic arthritis (PsA) is unknown, and the effectiveness of current drug treatments is unsatisfactory. In March 2019, the US Food and Drug Administration (FDA) approved risankizumab,...

Qin-Yi Su, Hao-Nan Zhou, Guo-Mei **a, Rui-Yuan Zhang… in Rheumatology and Therapy (2024)

Article

The role of nutrition in analysis of risk factors and short-term outcomes for late-onset necrotizing enterocolitis among very preterm infants: a nationwide, multicenter study in China

Necrotizing enterocolitis (NEC) is a serious gastrointestinal disease, primarily affects preterm newborns and occurs after 7 days of life (late-onset NEC, LO-NEC). Unfortunately, over the past several decades,...

Kun-Yao Hong, Yao Zhu, Fan Wu, Jian Mao, Ling Liu, Rong Zhang… in BMC Pediatrics (2024)

Article

‘Skip’ osteoporosis vertebral compression fractures caused by electrical injury: a case report and review of the literature

Electrical injuries rarely result in fractures, such as long bone fractures and spinal fractures. A few articles have reported osteoporosis vertebral compression fractures (OVCFs) caused by electrical injuries...

Ruili Jia, Yanhao Sun, Chong Liu, Rui-chao Liu… in Journal of Medical Case Reports (2024)

Article

Bone health and body composition in transgender adults before gender-affirming hormonal therapy: data from the COMET study

Preliminary data suggested that bone mineral density (BMD) in transgender adults before initiating gender-affirming hormone therapy (GAHT) is lower when compared to cisgender controls. In this study, we analyz...

C. Ceolin, A. Scala, M. Dall’Agnol… in Journal of Endocrinological Investigation (2024)

Article

Publisher Correction: Psittacosis caused severe community-acquired pneumonia accompanied by acute hypoxic respiratory failure: a multicenter retrospective cohort study from China

**ao Tang, Na Wang, Gang Liu, Hai Tan, Ai-Min Li, Yan-Qiu Gao… in BMC Infectious Diseases (2024)

Article

A network pharmacology approach to decipher the mechanism of total flavonoids from Dracocephalum Moldavica L. in the treatment of cardiovascular diseases

Cardiovascular disease (CVD) seriously endangers human health and is characterized by high mortality and disability. The effectiveness of Dracocephalum moldavica L. in the treatment of CVD has been proven by clin...

Rui-fang Zheng, Kaderyea Kader, Di-wei Liu… in BMC Complementary Medicine and Therapies (2024)

Article

Efficacy of various surgical approaches in treating hematospermia using transurethral seminal vesiculoscopy

To explore the efficacy of different approaches of seminal vesiculoscopy surgery and the predictive factors of good treatment outcome.

Rui-Jie Yao, Hong **ao, Shu-Shen Chen, Zhi-Hao Feng, Yi-Lang Ding, ** Chen… in BMC Surgery (2023)

Article

Associations of medicine use and ejection fraction with the coexistence of frailty and sarcopenia in a sample of heart failure outpatients: a cross-sectional study

Frailty and sarcopenia have been extensively studied in heart failure (HF) patients, but their coexistence is unknown. The aim of this work is to describe the coexistence of these conditions in a sample of HF ...

Rui Valdiviesso, Teresa F. Amaral, Emília Moreira… in BMC Cardiovascular Disorders (2023)

Article

Metatranscriptome of human lung microbial communities in a cohort of mechanically ventilated COVID-19 Omicron patients

The Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infected a substantial proportion of Chinese population, and understanding the factors underlying the severity of the dis...

Lin Wang, Jia-Bao Cao, Bin-Bin **a, Yue-Juan Li… in Signal Transduction and Targeted Therapy (2023)

Article

Dynamic single-cell map** unveils Epstein‒Barr virus-imprinted T-cell exhaustion and on-treatment response

Epstein‒Barr virus (EBV)-associated gastric cancer (GC) manifests an intriguing immunotherapy response. However, the cellular basis for EBV-imprinted tumour immunity and on-treatment response remains undefined...

Miao-Zhen Qiu, Chaoye Wang, Zhiying Wu, Qi Zhao… in Signal Transduction and Targeted Therapy (2023)

Article

Differentiation of pulmonary solid nodules attached to the pleura detected by thin-section CT

Pulmonary solid pleura-attached nodules (SPANs) are not very commonly detected and thus not well studied and understood. This study aimed to identify the clinical and CT characteristics for differentiating ben...

** Jiang, Fa-** Lv, Yang Tao, Bin-jie Fu, Wang-jia Li… in Insights into Imaging (2023)

Article

Real-world evidence regarding the growth of very premature infants with small for gestational age after birth: a multicenter survey in China

To analyze the real-world growth pattern of very premature infants (VPI) with small for gestational age (SGA) after birth by using the ΔZ value of weight at discharge.

Xue-Rong Huang, Wei Shen, Fan Wu, Jian Mao, Ling Liu, Yan-Mei Chang… in BMC Pediatrics (2023)

Article

Efficacy and safety of self-administered acupressure on symptoms, quality of life and nasal mucosal function in patients with perennial allergic rhinitis: study protocol for a randomized controlled exploratory trial

Allergic rhinitis is a global health problem that can potentially be managed through acupressure. Our clinical observations have identified Allergic Rhinitis Acupressure Therapeutic (ARAT) as a novel acupressu...

Kai Li, Wei Huang, Rui-Jian Li, **ao-Cong Feng… in BMC Complementary Medicine and Therapies (2023)

Article

Metformin accelerates bone fracture healing by promoting type H vessel formation through inhibition of YAP1/TAZ expression

Due to increasing morbidity worldwide, fractures are becoming an emerging public health concern. This study aimed to investigate the effect of metformin on the healing of osteoporotic as well as normal fractur...

Zhe Ruan, Hao Yin, Teng-Fei Wan, Zhi-Rou Lin, Shu-Shan Zhao, Hai-Tao Long… in Bone Research (2023)

Article

Psittacosis caused severe community-acquired pneumonia accompanied by acute hypoxic respiratory failure: a multicenter retrospective cohort study from China

Psittacosis can cause severe community-acquired pneumonia (CAP). The clinical manifestations of psittacosis range from subclinical to fulminant psittacosis with multi-organ failure. It is essential to summariz...

**ao Tang, Na Wang, Gang Liu, Hai Tan, Ai-Min Li, Yan-Qiu Gao… in BMC Infectious Diseases (2023)

Article

Effects of mixed oil emulsion on short-term clinical outcomes in premature infants: A prospective, multicenter, randomized controlled trial

This study compared the clinical effects of two different lipid emulsions in premature infants with gestational age < 32 weeks (VPI) or birth weight < 1500 g (VLBWI) to provide an evidence-based medicine basis...

Qing Yang, Juan Kong, Rui-Miao Bai, Wen-Ting Yu… in European Journal of Clinical Nutrition (2023)