693 Result(s)
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Rui-** **ao
Life Sciences
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Article
Phylogenomics, divergence times and notes of orders in Basidiomycota
Basidiomycota is one of the major phyla in the fungal tree of life. The outline of Basidiomycota provides essential taxonomic information for researchers and workers in mycology. In this study, we present a ti...
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Open AccessPopulation structure and selection signal analysis of indigenous sheep from the southern edge of the Taklamakan Desert
Analyzing the genetic diversity and selection characteristics of sheep (Ovis aries) holds significant value in understanding their environmental adaptability, enhancing breeding efficiency, and achieving effec...
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Broadcasters, receivers, functional groups of metabolites, and the link to heart failure by revealing metabolomic network connectivity
Blood-based small molecule metabolites offer easy accessibility and hold significant potential for insights into health processes, the impact of lifestyle, and genetic variation on disease, enabling precise ri...
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Open AccessIntegration of large and diverse angiosperm DNA fragments into Asian Gnetum mitogenomes
Horizontal gene transfer (HGT) events have rarely been reported in gymnosperms. Gnetum is a gymnosperm genus comprising 25‒35 species sympatric with angiosperms in West African, South American, and Southeast Asia...
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Mendelian randomization evidence for the causal effect of mental well-being on healthy aging
Mental well-being relates to multitudinous lifestyle behaviours and morbidities and underpins healthy aging. Thus far, causal evidence on whether and in what pattern mental well-being impacts healthy aging and...
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Shoot and Root Traits are Associated with Varying Soil Phosphorus Supply in Chinese Cabbage
Purpose: Phosphorus (P) is an essential nutrient for crop growth. P absorption efficiency was closely correlated with the variety of crop traits. It is currently unclear how vegetable crops may adapt to variou...
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Open AccessMechanical models and measurement methods of solid stress in tumors
In addition to genetic mutations, biomechanical factors also affect the structures and functions of the tumors during tumor growth, including solid stress, interstitial fluid pressure, stiffness, and microarch...
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Open AccessEndothelial progenitor cell-derived extracellular vesicles: the world of potential prospects for the treatment of cardiovascular diseases
Cardiovascular diseases (CVDs) have emerged as a predominant threat to human health, surpassing the incidence and mortality rates of neoplastic diseases. Extracellular vesicles (EVs) serve as vital mediators i...
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Repair of tendons treated with peracetic acid–ethanol and gamma irradiation by EDC combined with NHS: a morphological, biochemical and biomechanical study in vitro
The purpose of this study was to investigate whether 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) combined with n-hydroxysuccinimide (NHS) can repair tendon damage caused by peracetic acid–ethanol and ...
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Article
Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2
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Article
The truncated AXIN1 isoform promotes hepatocellular carcinoma metastasis through SRSF9-mediated exon 9 skip**
Axis inhibitor protein 1 (AXIN1) is a protein recognized for inhibiting tumor growth and is commonly involved in cancer development. In this study, we explored the potential molecular mechanisms that connect a...
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Proteomics Sequencing Reveals the Role of TGF-β Signaling Pathway in the Peripheral Blood of Offspring Rats Exposed to Fluoride
The underlying mechanism of fluorosis has not been fully elucidated. The purpose of this study was to explore the mechanism of fluorosis induced by sodium fluoride (NaF) using proteomics. Six offspring rats ex...
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Computational tools for plant genomics and breeding
Plant genomics and crop breeding are at the intersection of biotechnology and information technology. Driven by a combination of high-throughput sequencing, molecular biology and data science, great advances h...
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Open AccessEstablishment of an in vitro model of monocyte-like THP-1 cells for trained immunity induced by bacillus Calmette-Guérin
Mycobacteria bloodstream infections are common in immunocompromised people and usually have disastrous consequences. As the primary phagocytes in the bloodstream, monocytes and neutrophils play critical roles ...
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Open AccessAnalysis of endophytic bacterial diversity in seeds of different genotypes of cotton and the suppression of Verticillium wilt pathogen infection by a synthetic microbial community
In agricultural production, fungal diseases significantly impact the yield and quality of cotton (Gossypium spp.) with Verticillium wilt posing a particularly severe threat.
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Article
Protective effect of resveratrol on nickel-refining fumes-induced inflammatory damage
Nickel (Ni), a ductile and hard silver-white transition metal, is commonly found in occupational environments and can harm the human body. Since it is a toxic compound, long-term Ni exposure can cause pneumoni...
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Open AccessThrombomodulin reduces α-synuclein generation and ameliorates neuropathology in a mouse model of Parkinson’s disease
The neurotoxic α-synuclein (α-syn) oligomers play an important role in the occurrence and development of Parkinson’s disease (PD), but the factors affecting α-syn generation and neurotoxicity remain unclear. W...
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Open AccessG6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1–Bax-mediated mitochondrial apoptosis pathway
Glucose-6-phosphate dehydrogenase (G6PD) plays an important role in vascular smooth muscle cell (VSMC) phenotypic switching, which is an early pathogenic event in various vascular remodeling diseases (VRDs). H...
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Open AccessKaryotype and LTR-RTs analysis provide insights into oak genomic evolution
Whole-genome duplication and long terminal repeat retrotransposons (LTR-RTs) amplification in organisms are essential factors that affect speciation, local adaptation, and diversification of organisms. Underst...
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Intercrop** efficiently utilizes phosphorus resource in soil via different strategies mediated by crop traits and species combination
Understanding how long-term intercrop** and phosphorus (P)-fertilizer application affect soil P fractions through P-acquisition strategies is critical to maintaining soil P balance in agroecosystems.
