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  1. Article

    Open Access

    High expression of RTEL1 predicates worse progression in gliomas and promotes tumorigenesis through JNK/ELK1 cascade

    Gliomas are the most common primary intracranial tumor worldwide. The maintenance of telomeres serves as an important biomarker of some subtypes of glioma. In order to investigate the biological role of RTEL1 ...

    Guanjie Wang, **aojuan Ren, Jianying Li, Rongrong Cui, Xumin Zhao, Fang Sui in BMC Cancer (2024)

  2. No Access

    Article

    Targeting JMJD1C to selectively disrupt tumor Treg cell fitness enhances antitumor immunity

    Regulatory T (Treg) cells are critical for immune tolerance but also form a barrier to antitumor immunity. As therapeutic strategies involving Treg cell depletion are limited by concurrent autoimmune disorders, i...

    Xuehui Long, Sulin Zhang, Yuliang Wang, **g**g Chen, Yanlai Lu in Nature Immunology (2024)

  3. Article

    Open Access

    Promoter methylation of transient receptor potential melastatin-related 7 (TRPM7) predicts a better prognosis in patients with Luminal A breast cancers

    Breast cancer is the most common female tumors arising worldwide, and genetic and epigenetic events are constantly accumulated in breast tumorigenesis. The melastatin-related transient receptor potential 7 cha...

    Yuanyuan Wang, Rong Lu, Pu Chen, Rongrong Cui, Meiju Ji, in BMC Cancer (2022)

  4. Article

    Open Access

    Co-expression of parathyroid hormone related protein and TGF-beta in breast cancer predicts poor survival outcome

    Better methods to predict prognosis can play a supplementary role in administering individualized treatment for breast cancer patients. Altered expressions of PTHrP and TGF-β have been observed in various type...

    Cheng Xu, Zhengyuan Wang, Rongrong Cui, Hongyu He, **aoyan Lin, Yuan Sheng in BMC Cancer (2015)