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Article
Open AccessMicrostimulation of human somatosensory cortex evokes task-dependent, spatially patterned responses in motor cortex
The primary motor (M1) and somatosensory (S1) cortices play critical roles in motor control but the signaling between these structures is poorly understood. To fill this gap, we recorded – in three participant...
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Article
Open AccessClosed-loop stimulation of lateral cervical spinal cord in upper-limb amputees to enable sensory discrimination: a case study
Modern myoelectric prosthetic hands have multiple independently controllable degrees of freedom, but require constant visual attention to use effectively. Somatosensory feedback provides information not availa...
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Article
Open AccessThe effect of wrist posture on extrinsic finger muscle activity during single joint movements
Wrist posture impacts the muscle lengths and moment arms of the extrinsic finger muscles that cross the wrist. As a result, the electromyographic (EMG) activity associated with digit movement at different wris...
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Article
Open AccessRecording single- and multi-unit neuronal action potentials from the surface of the dorsal root ganglion
The dorsal root ganglia (DRG) contain cell bodies of primary afferent neurons, which are frequently studied by recording extracellularly with penetrating microelectrodes inserted into the DRG. We aimed to isol...
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Article
Open AccessEffects of Synchronous Electrode Pulses on Neural Recruitment During Multichannel Microstimulation
The recent proliferation of high-density microelectrode arrays has inspired several new applications of electrical microstimulation, including restoration of sensory functions in the visual, auditory, and soma...
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Article
Open AccessMotor cortical activity changes during neuroprosthetic-controlled object interaction
Brain-computer interface (BCI) controlled prosthetic arms are being developed to restore function to people with upper-limb paralysis. This work provides an opportunity to analyze human cortical activity durin...
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Chapter
Nanostructured Coatings for Improved Charge Delivery to Neurons
This chapter explores the variability and limitations of traditional stimulation electrodes by first appreciating how electrical potential differences lead to efficacious activation of nearby neurons and exami...