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Mosquito brains encode unique features of human odour to drive host seeking

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  1. Article

    Open Access

    Mosquito odour-baited mass trap** reduced malaria transmission intensity: a result from a controlled before-and-after intervention study

    Conventional vector control strategies have significantly reduced the malaria burden. The sustainability of these methods is currently challenged. Odour-based traps are emerging technologies that can complemen...

    Yared Debebe, Habte Tekie, Sisay Dugassa, Richard J. Hopkins in BMC Medicine (2024)

  2. Article

    Open Access

    Adenosine triphosphate overrides the aversive effect of antifeedants and toxicants: a model alternative phagostimulant for sugar-based vector control tools

    Sugar, when used as the phagostimulant in attractive toxic bait control tools, limits the efficacy and selectivity of this technology. Thus, more potent and selective phagostimulants than sugar are required to...

    Matthew Lukenge, Rickard Ignell, Sharon Rose Hill in Parasites & Vectors (2023)

  3. Article

    Open Access

    Effect of non-human hosts on the human biting rate of primary and secondary malaria vectors in Tanzania

    Malaria vectors vary in feeding preference depending on their innate behaviour, host availability and abundance. Host preference and human biting rate in malaria vectors are key factors in establishing zooprop...

    Godfrey C. Katusi, Marie R. G. Hermy, Samwely M. Makayula in Malaria Journal (2023)

  4. Article

    Open Access

    Odour-mediated oviposition site selection in Aedes aegypti depends on aquatic stage and density

    Olfaction plays an important role in the selection and assessment of oviposition sites by mosquitoes. Volatile organic compounds (VOCs) associated with potential breeding sites affect the behaviour of gravid m...

    Zaid Khan, Björn Bohman, Rickard Ignell, Sharon Rose Hill in Parasites & Vectors (2023)

  5. Article

    Open Access

    Distance from human dwellings differentially affects the efficacy of a synthetic cattle urine odour lure to trap malaria vectors

    Cost–effective outdoor–based devices for surveillance and control of outdoor mosquito vector populations can substantially improve their efficacy when baited with synthetic human and animal odours. This study ...

    Godfrey C. Katusi, Samwely M. Makayula, Nicodem J. Govella in Malaria Journal (2023)

  6. Article

    Open Access

    Seasonal variation in abundance and blood meal sources of primary and secondary malaria vectors within Kilombero Valley, Southern Tanzania

    Existing control tools have significantly reduced malaria over the past two decades. However, progress has been stalled due to increased resistance in primary vectors and the increasing role of secondary vecto...

    Godfrey C. Katusi, Marie R. G. Hermy, Samwely M. Makayula in Parasites & Vectors (2022)

  7. Article

    Open Access

    Natural plant diet impacts phenotypic expression of pyrethroid resistance in Anopheles mosquitoes

    Success in reducing malaria transmission through vector control is threatened by insecticide resistance in mosquitoes. Although the proximal molecular mechanisms and genetic determinants involved are well docu...

    Prisca S. L. Paré, Domonbabele F. D. S. Hien, Koama Bayili in Scientific Reports (2022)

  8. Article

    Open Access

    Mosquito host-seeking diel rhythm and chemosensory gene expression is affected by age and Plasmodium stages

    Malaria parasites can affect vector-related behaviours, increasing transmission success. Using Anopheles gambiae and Plasmodium falciparum, we consider the effect of interaction between infection stage and vector...

    Melika Hajkazemian, Sharon R. Hill, Raimondas Mozūraitis in Scientific Reports (2022)

  9. Article

    Open Access

    Malaria mosquitoes acquire and allocate cattle urine to enhance life history traits

    Nutrient acquisition and allocation integrate foraging and life-history traits in insects. To compensate for the lack of a particular nutrient at different life stages, insects may acquire these through supple...

    Mengistu Dawit, Sharon R. Hill, Göran Birgersson, Habte Tekie in Malaria Journal (2022)

  10. Article

    Open Access

    Cattle-Derived Unsaturated Aldehydes Repel Biting Midges and Mosquitoes

    Host-derived repellents offer a novel way to reduce disease vector–host interactions, particularly for vectors and nuisance pests where commercial repellents are not available, e.g., Culicoides biting midges. By ...

    Elin Isberg, Rickard Ignell in Journal of Chemical Ecology (2022)

  11. Article

    Open Access

    Contrasting effects of the alkaloid ricinine on the capacity of Anopheles gambiae and Anopheles coluzzii to transmit Plasmodium falciparum

    Besides feeding on blood, females of the malaria vector Anopheles gambiae sensu lato readily feed on natural sources of plant sugars. The impact of toxic secondary phytochemicals contained in plant-derived sugars...

    Domonbabele F. D. S. Hien, Prisca S. L. Paré, Amanda Cooper in Parasites & Vectors (2021)

  12. Article

    Open Access

    Development of a chimeric odour blend for attracting gravid malaria vectors

    Odour-based tools targeting gravid malaria vectors may complement existing intervention strategies. Anopheles arabiensis are attracted to, and stimulated to oviposit by, natural and synthetic odours of wild and d...

    Betelehem Wondwosen, Mengistu Dawit, Yared Debebe, Habte Tekie in Malaria Journal (2021)

  13. Article

    Open Access

    Regulation of the antennal transcriptome of the dengue vector, Aedes aegypti, during the first gonotrophic cycle

    In the light of dengue being the fastest growing transmissible disease, there is a dire need to identify the mechanisms regulating the behaviour of the main vector Aedes aegypti. Disease transmission requires the...

    Sharon Rose Hill, Tanvi Taparia, Rickard Ignell in BMC Genomics (2021)

  14. Article

    Open Access

    Modulation of odour-guided behaviour in mosquitoes

    Mosquitoes are emerging as model systems with which to study innate behaviours through neuroethology and functional genomics. Decades of work on these disease vectors have provided a solid behavioural framewor...

    Sharon R. Hill, Rickard Ignell in Cell and Tissue Research (2021)

  15. Article

    Open Access

    Malaria hotspots explained from the perspective of ecological theory underlying insect foraging

    Hotspots constitute the major reservoir for residual malaria transmission, with higher malaria incidence than neighbouring areas, and therefore, have the potential to form the cornerstone for successful interv...

    Yared Debebe, Sharon Rose Hill, Habte Tekie, Sisay Dugassa in Scientific Reports (2020)

  16. Article

    Open Access

    Comparative morphological and transcriptomic analyses reveal chemosensory genes in the poultry red mite, Dermanyssus gallinae

    Detection of chemical cues via chemosensory receptor proteins are essential for most animals, and underlies critical behaviors, including location and discrimination of food resources, identification of sexual...

    Biswajit Bhowmick, Yu Tang, Fang Lin, Øivind Øines, Jianguo Zhao in Scientific Reports (2020)

  17. Article

    Open Access

    Plasmodium falciparum gametocyte-induced volatiles enhance attraction of Anopheles mosquitoes in the field

    Plasmodium parasites manipulate the interaction between their mosquito and human hosts. Patients infected with gametocytes attract anopheline mosquitoes differentially compared to healthy individuals, an effect a...

    Yared Debebe, Sharon Rose Hill, Göran Birgersson, Habte Tekie in Malaria Journal (2020)

  18. Article

    Open Access

    Sex and age modulate antennal chemosensory-related genes linked to the onset of host seeking in the yellow-fever mosquito, Aedes aegypti

    The mosquito Aedes aegypti is the primary vector for the fastest growing infectious disease in the world, dengue fever. Disease transmission heavily relies on the ability of female mosquitoes to locate their huma...

    Anaïs Karine Tallon, Sharon Rose Hill, Rickard Ignell in Scientific Reports (2019)

  19. Article

    Open Access

    Shady business: understanding the spatial ecology of exophilic Anopheles mosquitoes

    Understanding the ecology of exophilic anophelines is a key step toward develo** outdoor control strategies to complement existing indoor control tools against malaria vectors. This study was conducted to as...

    Yared Debebe, Sharon R. Hill, Habte Tekie, Rickard Ignell in Malaria Journal (2018)

  20. Article

    Open Access

    Sweet attraction: sugarcane pollen-associated volatiles attract gravid Anopheles arabiensis

    Anopheles arabiensis is a key vector for the transmission of human malaria in sub-Saharan Africa. Over the past 10,000 years, humans have successfully cultivated grasses and altered the landscape, creating An. ar...

    Betelehem Wondwosen, Göran Birgersson, Habte Tekie, Baldwyn Torto in Malaria Journal (2018)

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