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  1. Article

    Open Access

    Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated proteins

    Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing methods for estimating the probability of mot...

    Norman E Davey, Richard J Edwards, Denis C Shields in BMC Bioinformatics (2010)

  2. Article

    Open Access

    GASP: Gapped Ancestral Sequence Prediction for proteins

    The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a simple procedure and relies on accurate align...

    Richard J Edwards, Denis C Shields in BMC Bioinformatics (2004)