22 Result(s)
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Article
Timing After Neoadjuvant Therapy Predicts Mortality in Patients Undergoing Esophagectomy: a Propensity Score–Matched Analysis
Currently most surgeons allow 6–12 weeks after neoadjuvant therapy prior to recommending esophagectomy. Given that complete pathologic response correlates to improved survival, some have advocated a longer int...
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Article
The use of indocyanine green (ICYG) angiography intraoperatively to evaluate gastric conduit perfusion during esophagectomy: does it impact surgical decision-making?
Ischemia is known to be a major contributor for anastomotic leaks and indocyanine green (ICYG) fluorescence angiography has been utilized to assess perfusion. Experienced esophageal surgeons have clinically as...
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Article
Comparative outcomes of laparoscopic and robotic approaches to gastrectomy: a National Cancer Database study
Gastric cancer is associated with significant mortality worldwide. Radical gastrectomy with lymphadenectomy is considered the only curative option. Traditionally, these operations are associated with significa...
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Article
Comparative Perioperative Outcomes by Esophagectomy Surgical Technique
Surgical resection is vital in the curative management of patients with esophageal cancer. However, a myriad of surgical procedures exists based on surgeon preference and training. We report on the perioperati...
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Article
Comparative outcomes of minimally invasive and robotic-assisted esophagectomy
Minimally invasive esophagectomy (MIE) has demonstrated superior outcomes compared to open approaches. The myriad of techniques has precluded the recommendation of a standard approach. The addition of robotics...
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Article
Chemoradiation and Local Excision for T2N0 Rectal Cancer Offers Equivalent Overall Survival Compared to Standard Resection: a National Cancer Database Analysis
Local excision (LE) alone is associated with worse survival compared to radical surgery (RS) for T2 rectal cancer, but LE with additional chemoradiation (CRT) may improve outcomes. The objective of this study ...
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Article
Comparative long-term outcomes of upfront resected pancreatic cancer after preoperative biliary drainage
We evaluated whether preoperative biliary drainage was predictive of recurrence and survival among patients with resectable pancreatic cancer.
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Article
Effect of Body Mass Index in Patients Undergoing Resection for Gastric Cancer: A Single Center US Experience
With rising obesity in the USA, the impact of body mass index (BMI) on survival in gastric cancer remains unclear.
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Article
Prognostic Impact of Lymph Node Retrieval and Ratio in Gastric Cancer: a U.S. Single Center Experience
Increased lymph node (LN) retrieval for gastric cancer has been associated with improved overall survival (OS). This study examines the impact of number of examined LN (eLN) and lymph node ratio.
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Article
Curative Treatment of Esophageal Cancer; An Evidenced Based Review
In 2013, roughly 18,000 cases of esophageal cancer will be diagnosed in the United States with more than 15,000 people dying from the disease. Worldwide, an estimated 482,300 new esophageal cancer cases were d...
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Article
Extent of Lymphadenectomy Does Not Predict Survival in Patients Treated with Primary Esophagectomy
The number of lymph nodes resected and its impact on survival for patients with esophageal cancer remains undefined. Current guidelines recommend extended lymphadenectomy in patients not receiving neoadjuvant ...
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Article
Initial experience from a large referral center with robotic-assisted Ivor Lewis esophagogastrectomy for oncologic purposes
We report our initial experience of patients undergoing robotic-assisted Ivor Lewis esophagogastrectomy (RAIL) for oncologic purposes at a large-referral center.
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Article
Defining the Learning Curve for Robotic-assisted Esophagogastrectomy
The expansion of robotic-assisted surgery is occurring quickly, though little is generally known about the “learning curve” for the technology with utilization for complex esophageal procedures. The purpose of...
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Article
Adjuvant Radiation Therapy and Lymphadenectomy in Esophageal Cancer: A SEER Database Analysis
This study seeks to determine the effects of postoperative radiation therapy and lymphadenectomy on survival in esophageal cancer.
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Article
Outcomes of definitive or preoperative IMRT chemoradiation for esophageal cancer
Intensity-modulated radiation therapy (IMRT) is evolving for the treatment of gastrointestinal cancers. The purpose of this study is to analyze our outcomes utilizing IMRT chemoradiation for esophageal cancer.
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Article
Induction gemcitabine-based chemotherapy and neoadjuvant stereotactic body radiation therapy achieve high margin-negative resection rates for borderline resectable pancreatic cancer
Patients with borderline resectable pancreatic cancer (BRPC) have a higher probability of undergoing margin-negative resection after completing neoadjuvant therapy. Here, we describe a novel neoadjuvant approa...
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Article
Body Mass Index and Survival in Esophageal Adenocarcinoma Treated with Chemoradiotherapy Followed by Esophagectomy
Body mass index (BMI) has been linked with inferior outcomes in gastrointestinal malignancies. The purpose of this study is to evaluate the effect of BMI on survival in patients with esophageal adenocarcinoma.
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Article
Outcomes of anal cancer treated with definitive IMRT-based chemoradiation
Despite excellent long-term outcomes, definitive chemoradiation (CRT) for squamous cell carcinoma (SqCC) of the anal canal with traditional radiotherapy techniques results in significant morbidity. Accruing da...
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Chapter
Cholangiocarcinoma
Cholangiocarcinoma (CC) is a malignant neoplasm of bile duct epithelium.
Intrahepatic...
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Article
Cystatin M suppresses the malignant phenotype of human MDA-MB-435S cells
Proteases are involved in many aspects of tumor progression, including cell survival and proliferation, escape from immune surveillance, cell adhesion and migration, remodeling and invasion of the extracellula...
